Synthesis of Certain α-Amino Acid Esters from Malonic Ester1

JC Shivers, CR Hauser

Index: Shivers; Hauser Journal of the American Chemical Society, 1947 , vol. 69, p. 1265

Full Text: HTML

Citation Number: 13

Abstract

Method (B) has been described by Bouveault and Locquin, 6 and Hamlin and Hart~ ng,~ although yields are not reported for the last step. These workers developed the method primarily for the preparation of amino acids which they obtained by the hydrolysis of the oximino ester and reduction of the resulting oximino acid. 7 Method (A) has been indicated by Fischer and\ L'eigert* for the preparation of the ethyl ester of lysine, although they did ...