Generation and cyclization of a benzyne-tethered alkyllithium: preparation of 4-substituted indans
WF Bailey, SC Longstaff
Index: Bailey, William F.; Longstaff, Sarah C. Journal of Organic Chemistry, 1998 , vol. 63, # 3 p. 432 - 433
Full Text: HTML
Citation Number: 49
Abstract
The intramolecular addition of an organolithium to a tethered benzyne intermediate, illustrated below, offers a conceptually simple route to functionalized benzo-fused carbocycles. Although intermolecular addition of an organolithium to a benzyne is a well characterized process, 1 and while intramolecular trapping of benzyne intermediates by tethered heteroatomic nucleophiles or a stabilized carbanions, first demonstrated by ...
Related Articles:
[Olah, George A.; Arvanaghi, Massoud; Ohannesian, Lena Synthesis, 1986 , # 9 p. 770 - 772]
[Miyaura, Norio; Ishiyama, Tatsuo; Sasaki, Hirotomo; Ishikawa, Masako; Satoh, Makoto; Suzuki, Akira Journal of the American Chemical Society, 1989 , vol. 111, # 1 p. 314 - 321]
Formation of benzo-fused carbocycles by formal radical cyclization onto an aromatic ring
[Clive, Derrick L. J.; Sunasee, Rajesh Organic Letters, 2007 , vol. 9, # 14 p. 2677 - 2680]
Iridium??catalyzed direct dehydroxylation of alcohols
[Huang, Jian-Lin; Dai, Xi-Jie; Li, Chao-Jun European Journal of Organic Chemistry, 2013 , # 29 p. 6496 - 6500]
The active role of NHC ligands in platinum-mediated tandem hydroboration–cross coupling reactions
[Lillo, Vanesa; Mata, Jose A.; Segarra, Anna M.; Peris, Eduardo; Fernandez, Elena Chemical Communications, 2007 , # 21 p. 2184 - 2186]