CPI-905

Modify Date: 2024-02-02 11:34:34

CPI-905 Structure
CPI-905 structure
Common Name CPI-905
CAS Number 931078-17-0 Molecular Weight 344.36
Density N/A Boiling Point N/A
Molecular Formula C18H20N2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CPI-905


CPI-905 is a potent and selective EZH2 inhibitor with IC50 value of 39.5 nM.

 Names

Name CPI-905

 CPI-905 Biological Activity

Description CPI-905 is a potent and selective EZH2 inhibitor with IC50 value of 39.5 nM.
References 1. Bradley WD, Arora S, Busby J, Balasubramanian S, Gehling VS, Nasveschuk CG, Vaswani RG, Yuan CC, Hatton C, Zhao F, Williamson KE, Iyer P, Méndez J, Campbell R, Cantone N, Garapaty-Rao S, Audia JE, Cook AS, Dakin LA, Albrecht BK, Harmange JC, Daniels DL, Cummings RT, Bryant BM, Normant E, Trojer P. EZH2 inhibitor efficacy in non-Hodgkin's lymphoma does not require suppression of H3K27 monomethylation. Chem Biol. 2014 Nov 20;21(11):1463-75. doi: 10.1016/j.chembiol.2014.09.017. PubMed PMID: 25457180.

 Chemical & Physical Properties

Molecular Formula C18H20N2O5
Molecular Weight 344.36
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