Metronidazole-d3

Modify Date: 2024-01-02 19:13:30

Metronidazole-d3 structure	Common Name	Metronidazole-d3
	CAS Number	83413-09-6	Molecular Weight	174.17
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₆H₆D₃N₃O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Metronidazole-d3

Metronidazole-d3 is deuterium labeled Metronidazole.

Name	Metronidazole-d3

Description	Metronidazole-d3 is deuterium labeled Metronidazole.
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. In Schaechter, M.; Engleberg, N. C.; DiRita, V. J. et al. Schaechter's Mechanisms of Microbial Disease. Hagerstown, MD: Lippincott Williams & Wilkins. p. 28. [3]. http://www.drugs.com/monograph/metronidazole.html [4]. Cohen, S.H., et al., Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of America (SHEA) and the infectious diseases society of America (IDSA). Infect Control Hosp Epidemiol, 2010. 31(5): p. 431-55.

Molecular Formula	C₆H₆D₃N₃O₃
Molecular Weight	174.17
Exact Mass	174.08300
PSA	83.87000
LogP	0.61520