Boc-NH-O-C1-NHS ester
Modify Date: 2024-01-08 10:56:32
Boc-NH-O-C1-NHS ester structure
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Common Name | Boc-NH-O-C1-NHS ester | ||
|---|---|---|---|---|
| CAS Number | 80366-85-4 | Molecular Weight | 288.25400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C11H16N2O7 | Melting Point | 114 °C | |
| MSDS | N/A | Flash Point | N/A | |
Use of Boc-NH-O-C1-NHS esterBoc-NH-O-C1-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | (2,5-dioxopyrrolidin-1-yl) 2-[(2-methylpropan-2-yl)oxycarbonylamino]oxyacetate |
|---|---|
| Synonym | More Synonyms |
| Description | Boc-NH-O-C1-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Melting Point | 114 °C |
|---|---|
| Molecular Formula | C11H16N2O7 |
| Molecular Weight | 288.25400 |
| Exact Mass | 288.09600 |
| PSA | 114.73000 |
| LogP | 0.19220 |
|
~92%
Boc-NH-O-C1-NHS... CAS#:80366-85-4 |
| Literature: Deroo, Stephanie; Defrancq, Eric; Moucheron, Cecile; Kirsch-De Mesmaeker, Andree; Dumy, Pascal Tetrahedron Letters, 2003 , vol. 44, # 46 p. 8379 - 8382 |
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~%
Boc-NH-O-C1-NHS... CAS#:80366-85-4 |
| Literature: Deroo, Stephanie; Defrancq, Eric; Moucheron, Cecile; Kirsch-De Mesmaeker, Andree; Dumy, Pascal Tetrahedron Letters, 2003 , vol. 44, # 46 p. 8379 - 8382 |
![6-[[2-[(2-methylpropan-2-yl)oxycarbonylamino]oxyacetyl]amino]hexanoic acid structure](https://www.chemsrc.com/caspic/442/879898-82-5.png)
CAS#:879898-82-5| t-Boc-aminooxyacetic Acid N-Hydroxysuccinimide Ester |
| tBoc-aminooxyacetyl N-hydroxysuccinimide ester |
| N'-Boc-aminooxyacetyl N-hydroxysuccinimide ester |
| tBoc-AO-OSu |
| 2-tert-butoxycarbonylaminoxy-acetic acid 2,5-dioxo-pyrrolidin-1-yl ester |