HO-PEG8-CH2COOH

Modify Date: 2024-01-09 13:02:31

HO-PEG8-CH2COOH structure	Common Name	HO-PEG8-CH2COOH
	CAS Number	780006-30-6	Molecular Weight	428.47
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₃₆O₁₁	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of HO-PEG8-CH2COOH

HO-PEG8-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	HO-PEG8-CH2COOH

Description	HO-PEG8-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₈H₃₆O₁₁
Molecular Weight	428.47