Dibromobimane

Modify Date: 2024-01-14 15:20:51

Dibromobimane Structure
Dibromobimane structure
Common Name Dibromobimane
CAS Number 68654-25-1 Molecular Weight 350.00700
Density 1.98g/cm3 Boiling Point 371.8ºC at 760mmHg
Molecular Formula C10H10Br2N2O2 Melting Point 170-172ºC(lit.)
MSDS Chinese USA Flash Point 178.6ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of Dibromobimane


Dibromobimane is a thiol-selective fluorescent imaging agent. Dibromobimane is used to crosslink cysteine- and homocysteine-containing peptides[1].

 Names

Name dibromobimane
Synonym More Synonyms

 Dibromobimane Biological Activity

Description Dibromobimane is a thiol-selective fluorescent imaging agent. Dibromobimane is used to crosslink cysteine- and homocysteine-containing peptides[1].
Related Catalog
References

[1]. Aimee J Horsfall, et al. A Bimane-Based Peptide Staple for Combined Helical Induction and Fluorescent Imaging. Chembiochem. 2020 Dec 1;21(23):3423-3432.

 Chemical & Physical Properties

Density 1.98g/cm3
Boiling Point 371.8ºC at 760mmHg
Melting Point 170-172ºC(lit.)
Molecular Formula C10H10Br2N2O2
Molecular Weight 350.00700
Flash Point 178.6ºC
Exact Mass 347.91100
PSA 42.96000
LogP 1.60360
Index of Refraction 1.677
Storage condition 2~8°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport

 Synthetic Route

~76%

Dibromobimane Structure

Dibromobimane

CAS#:68654-25-1

Literature: Kosower,E.M.; Pazhenchevsky,B. Journal of the American Chemical Society, 1980 , vol. 102, p. 4983

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Dibromobimane Structure

Dibromobimane

CAS#:68654-25-1

Literature: Journal of the American Chemical Society, , vol. 102, p. 4983

~%

Dibromobimane Structure

Dibromobimane

CAS#:68654-25-1

Literature: Journal of the American Chemical Society, , vol. 102, p. 4983

~%

Dibromobimane Structure

Dibromobimane

CAS#:68654-25-1

Literature: Journal of the American Chemical Society, , vol. 102, p. 4983

~2%

Dibromobimane Structure

Dibromobimane

CAS#:68654-25-1

Literature: Journal of the American Chemical Society, , vol. 102, p. 4983

 Articles30

More Articles
Thiol labeling with bromobimanes.

Meth. Enzymol. 143 , 76, (1987)

Bromobimanes--fluorescent labeling agents for histochemical detection of sulfur containing neuropeptides in semithin sections.

Histochemistry 86 , 281, (1987)

Sulfur containing neuropeptides could be demonstrated in semithin sections of invertebrate nervous tissue, especially of gastropods, by using the bromobimanes as fluorescent labeling agents for thiol ...

Physicochemical changes in phosphorylase kinase induced by its cationic activator Mg(2+).

Protein Sci. 22(4) , 444-54, (2013)

For over four decades free Mg(2+) ions, that is, those in excess of MgATP, have been reported to affect a wide variety of properties of phosphorylase kinase (PhK), including its affinity for other mol...

 Synonyms

Dibromobimane
1,7-bis(bromomethyl)-2,6-dimethylpyrazolo[1,2-a]pyrazole-3,5-dione
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