(Z)-p-cyano-α-Cyanostilbene

Modify Date: 2025-08-27 18:36:32

(Z)-p-cyano-α-Cyanostilbene Structure
(Z)-p-cyano-α-Cyanostilbene structure
Common Name (Z)-p-cyano-α-Cyanostilbene
CAS Number 54676-54-9 Molecular Weight 230.26
Density N/A Boiling Point N/A
Molecular Formula C16H10N2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (Z)-p-cyano-α-Cyanostilbene


(Z)-p-cyano-α-Cyanostilbene (compound 11), a phenantrene derivative, has antiproliferative activity. (Z)-p-cyano-α-Cyanostilbene shows significant selectivity against HeLa (IC50=0.21 µM) and HepG2 (IC50=0.230 µM) cells without cytotoxic against normal skin fibroblasts (IC50>100 µM)[1].

 Names

Name (Z)-4-(1-cyano-2-phenylvinyl)benzonitrile
Synonym More Synonyms

 (Z)-p-cyano-α-Cyanostilbene Biological Activity

Description (Z)-p-cyano-α-Cyanostilbene (compound 11), a phenantrene derivative, has antiproliferative activity. (Z)-p-cyano-α-Cyanostilbene shows significant selectivity against HeLa (IC50=0.21 µM) and HepG2 (IC50=0.230 µM) cells without cytotoxic against normal skin fibroblasts (IC50>100 µM)[1].
Related Catalog
References

[1]. Nataša Perin, et al. Antiproliferative activity and mode of action analysis of novel amino and amido substituted phenantrene and naphtho[2,1-b]thiophene derivatives. Eur J Med Chem. 2020 Jan 1;185:111833.

 Chemical & Physical Properties

Molecular Formula C16H10N2
Molecular Weight 230.26
Exact Mass 230.08400
PSA 47.58000
LogP 3.62246

 Synonyms

4-(1-cyano-2-phenylvinyl)benzonitrile
4-((Z)-1-Cyano-2-phenyl-vinyl)-benzonitrile
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