Glyceryl Tri(octanoate-d15)

Modify Date: 2024-01-05 10:10:16

Glyceryl Tri(octanoate-d15) Structure
Glyceryl Tri(octanoate-d15) structure
Common Name Glyceryl Tri(octanoate-d15)
CAS Number 352431-24-4 Molecular Weight 515.96
Density 1.0±0.1 g/cm3 Boiling Point 508.0±17.0 °C at 760 mmHg
Molecular Formula C27H5D45O6 Melting Point N/A
MSDS Chinese USA Flash Point 209.3±21.0 °C

 Use of Glyceryl Tri(octanoate-d15)


Tricaprilin-d15 is the deuterium labeled Tricaprilin. Tricaprilin (Trioctanoin) is used in study for patients with mild to moderate Alzheimer's disease and has a role as an anticonvulsant and a plant metabolite[1][2].

 Names

Name glyceryl tri(octanoate-d15)
Synonym More Synonyms

 Glyceryl Tri(octanoate-d15) Biological Activity

Description Tricaprilin-d15 is the deuterium labeled Tricaprilin. Tricaprilin (Trioctanoin) is used in study for patients with mild to moderate Alzheimer's disease and has a role as an anticonvulsant and a plant metabolite[1][2].
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Tricaprylin

[3]. Kwok MK, et al. Re-thinking Alzheimer's disease therapeutic targets using gene-based tests. EBioMedicine. 2018 Nov;37:461-470.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 508.0±17.0 °C at 760 mmHg
Molecular Formula C27H5D45O6
Molecular Weight 515.96
Flash Point 209.3±21.0 °C
Exact Mass 515.643188
PSA 78.90000
LogP 9.33
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.458

 Synonyms

Glyceryl Tri(octanoate-d15)
Propane-1,2,3-triyl tri(H)octanoate
1,2,3-Propanetriyl tri(H)octanoate
Octanoic-d acid, 1,2,3-propanetriyl ester