NLRP3-IN-21

Modify Date: 2024-01-14 03:44:28

NLRP3-IN-21 Structure
NLRP3-IN-21 structure
Common Name NLRP3-IN-21
CAS Number 2956791-61-8 Molecular Weight 529.32
Density N/A Boiling Point N/A
Molecular Formula C20H13Cl2F3N6O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NLRP3-IN-21


NLRP3-IN-21 (compound L38) is a NLRP3 inflammasome inhibitor with inflammatory properties. NLRP3-IN-21 inhibits NLRP3 inflammasome activation and pyroptosis by suppressing gasdermin D cleavage, ASC oligomerization, and NLRP3 inflammasome assembly[1].

 Names

Name NLRP3-IN-21

 NLRP3-IN-21 Biological Activity

Description NLRP3-IN-21 (compound L38) is a NLRP3 inflammasome inhibitor with inflammatory properties. NLRP3-IN-21 inhibits NLRP3 inflammasome activation and pyroptosis by suppressing gasdermin D cleavage, ASC oligomerization, and NLRP3 inflammasome assembly[1].
Related Catalog
References

[1]. Na Li, et al. Discovery of Triazinone Derivatives as Novel, Specific, and Direct NLRP3 Inflammasome Inhibitors for the Treatment of DSS-Induced Ulcerative Colitis. J Med Chem. 2023 Oct 12;66(19):13428-13451.  

 Chemical & Physical Properties

Molecular Formula C20H13Cl2F3N6O2S
Molecular Weight 529.32
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.