PHD-IN-2

Modify Date: 2025-11-25 10:54:18

PHD-IN-2 Structure
PHD-IN-2 structure
Common Name PHD-IN-2
CAS Number 2924182-42-1 Molecular Weight 501.54
Density N/A Boiling Point N/A
Molecular Formula C26H27N7O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PHD-IN-2


PHD-IN-2 (Compound 91) is a PHD antagonist (IC50: < 5 nM). PHD-IN-2 induces erythropoietin synthesis in HEP3B cells (EC50: <2.5 μM). PHD-IN-2 can be used for research of cardiovascular disorders, metabolic disorders, hematological disorders, pulmonary disorders, kidney disorders, liver disorders, wound healing disorders, and cancer[1].

 Names

Name PHD-IN-2

 PHD-IN-2 Biological Activity

Description PHD-IN-2 (Compound 91) is a PHD antagonist (IC50: < 5 nM). PHD-IN-2 induces erythropoietin synthesis in HEP3B cells (EC50: <2.5 μM). PHD-IN-2 can be used for research of cardiovascular disorders, metabolic disorders, hematological disorders, pulmonary disorders, kidney disorders, liver disorders, wound healing disorders, and cancer[1].
Related Catalog
References

[1]. Xiao DING, et al. Prolyl hydroxylase domain-containing protein (phd) inhibitors and uses thereof. Patent. US20230192723A1.

 Chemical & Physical Properties

Molecular Formula C26H27N7O4
Molecular Weight 501.54
InChIKey GWUYHNJGQULKDQ-UHFFFAOYSA-N
SMILES CC(C)(C)OC(=O)N1CC2(C1)CN(c1ccc3c(O)c(C(=O)NCc4ccc(C#N)nc4)ncc3n1)C2
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