MC4033

Modify Date: 2025-08-27 12:36:11

MC4033 structure	Common Name	MC4033
	CAS Number	28532-21-0	Molecular Weight	295.29
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₁₃N₃O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MC4033

MC4033 shows IC50s of 39.4 μM, 52.1 μM, 41 μM and 30.1 μM in HCT116, H1299, A549 and U937, respectively[1]. MC4033 (25, 50, 100, and 200 μM, 72 h) reduces the level of H4K16Ac in HT29 cells, suggesting its ability to inhibit KAT8 in cells[1].

Name	MC4033

Description	MC4033 shows IC50s of 39.4 μM, 52.1 μM, 41 μM and 30.1 μM in HCT116, H1299, A549 and U937, respectively[1]. MC4033 (25, 50, 100, and 200 μM, 72 h) reduces the level of H4K16Ac in HT29 cells, suggesting its ability to inhibit KAT8 in cells[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> Epigenetics >> Histone Acetyltransferase
Target	12.1μM (lysine acetyltransferase 8, KAT8)[1]
References	[1]. Fiorentino F, et al. First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8. J Med Chem. 2023 May 25;66(10):6591-6616

Molecular Formula	C₁₆H₁₃N₃O₃
Molecular Weight	295.29
InChIKey	WBHVGUYXAZIVHV-ZROIWOOFSA-N
SMILES	CC1=NN(c2ccc(C(=O)O)cc2)C(=O)C1=Cc1ccc[nH]1

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MC4033

Use of MC4033

Names

MC4033 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.