EGFR mutant-IN-2
Modify Date: 2024-01-22 17:44:01
EGFR mutant-IN-2 structure
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Common Name | EGFR mutant-IN-2 | ||
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| CAS Number | 2770009-06-6 | Molecular Weight | 556.60 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H27F3N6O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of EGFR mutant-IN-2EGFR mutant-IN-2 (Compound D51) is an EGFR mutant inhibitor. EGFR mutant-IN-2 inhibits the EGFRL858R/T790M/C797S mutant with an IC50 value of 14 nM. EGFR mutant-IN-2 inhibits the EGFRdel19/T790M/C797S mutant with an IC50 value of 62 nM. EGFR mutant-IN-2 has favorable PK parameters, safety properties, in vivo stability, and antitumor activity[1]. |
| Name | EGFR mutant-IN-2 |
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| Description | EGFR mutant-IN-2 (Compound D51) is an EGFR mutant inhibitor. EGFR mutant-IN-2 inhibits the EGFRL858R/T790M/C797S mutant with an IC50 value of 14 nM. EGFR mutant-IN-2 inhibits the EGFRdel19/T790M/C797S mutant with an IC50 value of 62 nM. EGFR mutant-IN-2 has favorable PK parameters, safety properties, in vivo stability, and antitumor activity[1]. |
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| Molecular Formula | C27H27F3N6O2S |
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| Molecular Weight | 556.60 |