Pleconaril-d4

Modify Date: 2024-01-10 17:25:43

Pleconaril-d4 Structure
Pleconaril-d4 structure
Common Name Pleconaril-d4
CAS Number 2749329-20-0 Molecular Weight 385.37
Density N/A Boiling Point N/A
Molecular Formula C18H14D4F3N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pleconaril-d4


Pleconaril-d4 is deuterium labeled Pleconaril.

 Names

Name Pleconaril-d4

 Pleconaril-d4 Biological Activity

Description Pleconaril-d4 is deuterium labeled Pleconaril.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Benschop KS, et al. Genetic and antigenic structural characterization for resistance of echovirus 11 to pleconaril in an immunocompromised patient. J Gen Virol. 2015 Mar;96(Pt 3):571-9.

[3]. Lacroix C, et al. http://www.ncbi.nlm. In vitro characterisation of a pleconaril/pirodavir-like compound with potent activity against rhinoviruses. Virol J. 2015 Jul 14;12:106.

 Chemical & Physical Properties

Molecular Formula C18H14D4F3N3O3
Molecular Weight 385.37