Glyphosate-d2

Modify Date: 2024-01-08 10:45:07

Glyphosate-d2 Structure
Glyphosate-d2 structure
Common Name Glyphosate-d2
CAS Number 2733532-11-9 Molecular Weight 171.09
Density N/A Boiling Point N/A
Molecular Formula C3H6D2NO5P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Glyphosate-d2


Glyphosate-d2 is the deuterium labeled Glyphosate. Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants[1].

 Names

Name Glyphosate-d2

 Glyphosate-d2 Biological Activity

Description Glyphosate-d2 is the deuterium labeled Glyphosate. Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Greim H, et al. Evaluation of carcinogenic potential of the herbicide glyphosate, drawing on tumor incidence data from fourteen chronic/carcinogenicity rodent studies. Crit Rev Toxicol. 2015;45(3):185-208.

[3]. Zhang JW, et al The toxic effects and possible mechanisms of glyphosate on mouse oocytes. Chemosphere. 2019 Dec;237:124435.

 Chemical & Physical Properties

Molecular Formula C3H6D2NO5P
Molecular Weight 171.09