IRAK4-IN-10

Modify Date: 2024-01-10 21:22:57

IRAK4-IN-10 Structure
IRAK4-IN-10 structure
Common Name IRAK4-IN-10
CAS Number 2681278-09-9 Molecular Weight 400.48
Density N/A Boiling Point N/A
Molecular Formula C22H24N8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IRAK4-IN-10


IRAK4-IN-10 (compound 75) is a potent IRAK4 inhibitor with an IC50 of 1.5 nM. IRAK4-IN-10 blocks MyD88 dependent signaling. IRAK4-IN-9 has the potential for the research of inflammatory diseases, autoimmune diseases, and cancer[1].

 Names

Name IRAK4-IN-10

 IRAK4-IN-10 Biological Activity

Description IRAK4-IN-10 (compound 75) is a potent IRAK4 inhibitor with an IC50 of 1.5 nM. IRAK4-IN-10 blocks MyD88 dependent signaling. IRAK4-IN-9 has the potential for the research of inflammatory diseases, autoimmune diseases, and cancer[1].
Related Catalog
Target

IRAK4:1.5 nM (IC50)

References

[1]. Sabnis RW. Novel Tricyclic Heteroaryl Compounds as IRAK4 Inhibitors for Treating Cancer, Autoimmune and Inflammatory Diseases. ACS Med Chem Lett. 2022 Feb 28;13(3):336-337.

 Chemical & Physical Properties

Molecular Formula C22H24N8
Molecular Weight 400.48