JAK-IN-31

Modify Date: 2025-08-26 15:52:07

JAK-IN-31 Structure
JAK-IN-31 structure
Common Name JAK-IN-31
CAS Number 2597016-88-9 Molecular Weight 465.55
Density N/A Boiling Point N/A
Molecular Formula C21H19N7O2S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of JAK-IN-31


JAK-IN-31 (Example 75) is a JAK inhibitor with IC50 ranges of ≤0.01µM, ≤0.01µM, 0.01-0.1 µM and ≤0.01µM for JAK1, JAK2, JAK3 and Tyk2 respectively. JAK-IN-31 can be used in cancer research[1].

 Names

Name JAK-IN-31

 JAK-IN-31 Biological Activity

Description JAK-IN-31 (Example 75) is a JAK inhibitor with IC50 ranges of ≤0.01µM, ≤0.01µM, 0.01-0.1 µM and ≤0.01µM for JAK1, JAK2, JAK3 and Tyk2 respectively. JAK-IN-31 can be used in cancer research[1].
Related Catalog
References

[1]. David Randolph ANDERSON, et al. Substituted sulfonamide pyrrolopyridines as jak inhibitors. Patent WO2021022178A1.

 Chemical & Physical Properties

Molecular Formula C21H19N7O2S2
Molecular Weight 465.55
InChIKey YMJIHJWUUADELX-UHFFFAOYSA-N
SMILES Cc1nnc(-c2cnc3[nH]ccc3c2NC2CC(NS(=O)(=O)c3cccc(C#N)c3)C2)s1
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