Estrogen receptor α antagonist 1
Modify Date: 2024-09-18 17:15:02
Estrogen receptor α antagonist 1 structure
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Common Name | Estrogen receptor α antagonist 1 | ||
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| CAS Number | 2580941-45-1 | Molecular Weight | 452.54 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H32N2O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Estrogen receptor α antagonist 1Estrogen receptor α antagonist 1 (compound 35) is a highly selective antagonist of estrogen receptor α, with IC50s of 0.02, 6.55 and 7.73 μM for estrogen receptor α, estrogen receptor β and MCF-7 cells, respectively. Estrogen receptor α antagonist 1 (compound 35) can be used for the research of cancer[1]. |
| Name | Estrogen receptor α antagonist 1 |
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| Description | Estrogen receptor α antagonist 1 (compound 35) is a highly selective antagonist of estrogen receptor α, with IC50s of 0.02, 6.55 and 7.73 μM for estrogen receptor α, estrogen receptor β and MCF-7 cells, respectively. Estrogen receptor α antagonist 1 (compound 35) can be used for the research of cancer[1]. |
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| Related Catalog | |
| Target |
IC50: 0.02 μM (Estrogen receptor α), 6.55 μM (Estrogen receptor β) and 7.73 μM (MCF-7 cells)[1] |
| In Vitro | Estrogen receptor α antagonist 1 (compound 35) (1 nM-100 μM; 72 h)selectively inhibites estrogen receptor α, estrogen receptor β and MCF-7 cells[1]. Cell Viability Assay[1] Cell Line: MCF-7 cells Concentration: 1 nM-100 μM Incubation Time: 72 hours Result: Exhibited IC50s of 0.02, 6.55 and 7.73 μM for estrogen receptor α, estrogen receptor β and MCF-7 cells, respectively at 72 hours. |
| References |
| Molecular Formula | C26H32N2O5 |
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| Molecular Weight | 452.54 |