N-Methyl-DL-valine

Modify Date: 2024-01-11 19:33:16

N-Methyl-DL-valine structure	Common Name	N-Methyl-DL-valine
	CAS Number	2566-32-7	Molecular Weight	167.634
	Density	0.995	Boiling Point	N/A
	Molecular Formula	C₆H₁₄ClNO₂	Melting Point	82-84ºC
	MSDS	USA	Flash Point	N/A

Use of N-Methyl-DL-valine

N-Methyl-DL-valine is a valine derivant, is metabolized to cysteine, alanine, tyrosine, tryptophan, citric acid, and succinic acid in the sprout. N-Methyl-DL-valine involves in the modification of monomethyl auristatin F (MMAF), an anti-tubulin agent, makes it hydrophobic functionalization and increases cell permeability[1][2].

Name	N-methylvaline
Synonym	More Synonyms

Description	N-Methyl-DL-valine is a valine derivant, is metabolized to cysteine, alanine, tyrosine, tryptophan, citric acid, and succinic acid in the sprout. N-Methyl-DL-valine involves in the modification of monomethyl auristatin F (MMAF), an anti-tubulin agent, makes it hydrophobic functionalization and increases cell permeability[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. M. Pasteels, et al. Uptake and metabolism of [14C]rinderine and [14C]retronecine in leaf-beetles of the genus Platyphora and alkaloid accumulation in the exocrine defensive secretions. Chemoecology. 2003;13:55–62. [2]. Philip N Moquist, et al. Novel Auristatins with High Bystander and Cytotoxic Activities in Drug Efflux–positive Tumor Models. Mol Cancer Ther.2021;20(2): 320–328.

Description

Related Catalog

Research Areas >> Others

Signaling Pathways >> Others >> Others

References

[1]. M. Pasteels, et al. Uptake and metabolism of [14C]rinderine and [14C]retronecine in leaf-beetles of the genus Platyphora and alkaloid accumulation in the exocrine defensive secretions. Chemoecology. 2003;13:55–62.

[2]. Philip N Moquist, et al. Novel Auristatins with High Bystander and Cytotoxic Activities in Drug Efflux–positive Tumor Models. Mol Cancer Ther.2021;20(2): 320–328.

Density	0.995
Melting Point	82-84ºC
Molecular Formula	C₆H₁₄ClNO₂
Molecular Weight	167.634
Exact Mass	167.071304
PSA	49.33000
LogP	1.50790
Storage condition	Store at RT.

N-Methyl-DL-valine MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2922499990

HS Code	2922499990
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Investigation of 60Co γ-irradiated l-(−) malic acid, N-methyl-dl-valine and l-glutamic acid γ-ethyl ester by electron paramagnetic resonance technique Baskin, M.H., Aydin, M., and Osmanoğlu, S.

J. Mol. Struct. 983 , 200-202, (2010)

methyl-valine

N-Methylvaline hydrochloride

N-METHYL-DL-VALINE HYDROCHLORIDE

Valine, N-methyl-, hydrochloride (1:1)

H-(S,R)-NMeVal-OH

N-ME-DL-VAL-OH HCL

N-Methyl-dl-valine,HCl

N-methyl-valine

N-Methylvaline hydrochloride (1:1)

N-Methyl-DL-valine

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