P2X3 antagonist 38

Modify Date: 2024-01-03 21:44:57

P2X3 antagonist 38 Structure
P2X3 antagonist 38 structure
Common Name P2X3 antagonist 38
CAS Number 2545974-71-6 Molecular Weight 478.47
Density N/A Boiling Point N/A
Molecular Formula C22H25F3N6O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of P2X3 antagonist 38


P2X3 antagonist 38 (compound 4) is a potent and orally active P2X3 antagonist with IC50 values of 0.132, 0.165, 0.421 µM for hP2X3, rP2X3, gpP2X3, respectively[1].

 Names

Name P2X3 antagonist 38

 P2X3 antagonist 38 Biological Activity

Description P2X3 antagonist 38 (compound 4) is a potent and orally active P2X3 antagonist with IC50 values of 0.132, 0.165, 0.421 µM for hP2X3, rP2X3, gpP2X3, respectively[1].
Related Catalog
Target

P2X3 Receptor:0.132 μM (IC50)

References

[1]. YunFeng Chen, et al. N-carboxamidopyrazoline derivative serving as p2x3 receptor antagonist and applications. WO2022028154A1.

 Chemical & Physical Properties

Molecular Formula C22H25F3N6O3
Molecular Weight 478.47
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