c-Met-IN-13
Modify Date: 2025-08-25 20:32:43
c-Met-IN-13 structure
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Common Name | c-Met-IN-13 | ||
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| CAS Number | 2377724-93-9 | Molecular Weight | 550.55 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C30H28F2N2O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of c-Met-IN-13c-Met-IN-13 is a potent c-Met inhibitor with an IC50 value of 2.43 nM. c-Met-IN-13 shows excellent cytotoxicity for cancer cells. c-Met-IN-13 shows antiproliferative activity in a concentration- and time- dependent manner. c-Met-IN-13 has the potential for the research of cancer[1]. |
| Name | c-Met-IN-13 |
|---|
| Description | c-Met-IN-13 is a potent c-Met inhibitor with an IC50 value of 2.43 nM. c-Met-IN-13 shows excellent cytotoxicity for cancer cells. c-Met-IN-13 shows antiproliferative activity in a concentration- and time- dependent manner. c-Met-IN-13 has the potential for the research of cancer[1]. |
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| Related Catalog | |
| Target |
c-Met:2.43 nM (IC50) |
| In Vitro | c-Met-IN-13 (compound 10m) shows cytotoxic activities with IC50s of 0.14, 0.20, 0.26 µM for H460, HT-29, MKN-45, respectively[1]. c-Met-IN-13 shows tyrosine kinases selectively with IC50s of 4.42, 6.15, 18.64, 295, 540, >10000, 2.43 nM for c-kit, Flt-3,Ron, VEGFR-2, Flt-4, EGFR, C-Met, respectively[1]. c-Met-IN-13 (0-300 µg/ml; 72 h) shows antiproliferative activity in a concentration and time dependent manner[1]. |
| References |
| Molecular Formula | C30H28F2N2O6 |
|---|---|
| Molecular Weight | 550.55 |