7α,25-Dihydroxycholesterol-d6

Modify Date: 2024-01-14 20:30:34

7α,25-Dihydroxycholesterol-d6 Structure
7α,25-Dihydroxycholesterol-d6 structure
Common Name 7α,25-Dihydroxycholesterol-d6
CAS Number 2260669-11-0 Molecular Weight 424.69
Density N/A Boiling Point N/A
Molecular Formula C27H40D6O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 7α,25-Dihydroxycholesterol-d6


7α,25-Dihydroxycholesterol-d6 is deuterium labeled 7α,25-Dihydroxycholesterol. 7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol is highly

 Names

Name 7α,25-Dihydroxycholesterol-d6

 7α,25-Dihydroxycholesterol-d6 Biological Activity

Description 7α,25-Dihydroxycholesterol-d6 is deuterium labeled 7α,25-Dihydroxycholesterol. 7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol is highly
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[3].
References

[1]. Liu C, et al. Oxysterols direct B-cell migration through EBI2. Nature. 2011 Jul 27;475(7357):519-23.

[2]. Hannedouche S, et al. Oxysterols direct immune cell migration via EBI2. Nature. 2011 Jul 27;475(7357):524-7.

[3]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

 Chemical & Physical Properties

Molecular Formula C27H40D6O3
Molecular Weight 424.69