Anticancer agent 74

Modify Date: 2024-04-07 16:08:12

Anticancer agent 74 Structure
Anticancer agent 74 structure
Common Name Anticancer agent 74
CAS Number 2242503-82-6 Molecular Weight 351.44
Density N/A Boiling Point N/A
Molecular Formula C25H21NO Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Anticancer agent 74


Anticancer agent 74 is a moderate anticancer agent. Anticancer agent 74 has lower selectivity and cytotoxicity than doxorubicin to normal cell[1].

 Names

Name Anticancer agent 74

 Anticancer agent 74 Biological Activity

Description Anticancer agent 74 is a moderate anticancer agent. Anticancer agent 74 has lower selectivity and cytotoxicity than doxorubicin to normal cell[1].
Related Catalog
In Vitro Anticancer agent 74 has low cytotoxicity in HepG2 (IC50: 72.27 μM), A549 (IC50: 70.79 μM), HuCCA-1 (IC50: 70.42 μM) and MOLT-3 (IC50: 20.71 μM) cell lines. Anticancer agent 74 has low selectivity in HepG2 (IC50: 0.88 μM), A549 (IC50: 5.08 μM), HuCCA-1 (IC50: 5.11 μM) and MOLT-3 (IC50: 17.39 μM) cell lines[1]. Cell Cytotoxicity Assay Cell Line: A549, HuCCA-1, HepG2 and MOLT-3 cell lines Concentration: Incubation Time: Result: Had good cytotoxicity, low selectivity and cytotoxicity in all four primary cancer cell lines.
References

[1]. Bhornrawin Akkachairin, et al. Synthesis of neocryptolepines and carbocycle-fused quinolines and evaluation of their anticancer and antiplasmodial activities, Bioorg Chem. 2020 May;98:103732.

 Chemical & Physical Properties

Molecular Formula C25H21NO
Molecular Weight 351.44
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