Thalidomide-4-NH-PEG1-NH-Boc

Modify Date: 2023-02-27 18:07:39

Thalidomide-4-NH-PEG1-NH-Boc Structure
Thalidomide-4-NH-PEG1-NH-Boc structure
Common Name Thalidomide-4-NH-PEG1-NH-Boc
CAS Number 2154342-17-1 Molecular Weight 460.48
Density N/A Boiling Point N/A
Molecular Formula C22H28N4O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thalidomide-4-NH-PEG1-NH-Boc


Thalidomide-4-NH-PEG1-NH-Boc is a Boc-modified Thalidomide (HY-14658) that acts as a Cereblon ligand to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-4-NH-PEG1-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-4-NH-PEG1-NH-Boc is a key intermediate in the synthesis of CRBN-based PROTAC molecules.

 Names

Name Thalidomide-NH-PEG1-NH-Boc

 Thalidomide-4-NH-PEG1-NH-Boc Biological Activity

Description Thalidomide-4-NH-PEG1-NH-Boc is a Boc-modified Thalidomide (HY-14658) that acts as a Cereblon ligand to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-4-NH-PEG1-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-4-NH-PEG1-NH-Boc is a key intermediate in the synthesis of CRBN-based PROTAC molecules.
Related Catalog

 Chemical & Physical Properties

Molecular Formula C22H28N4O7
Molecular Weight 460.48
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