Cyclooctyne-O-amido-PEG2-NHS ester

Modify Date: 2025-08-25 21:13:45

Cyclooctyne-O-amido-PEG2-NHS ester Structure
Cyclooctyne-O-amido-PEG2-NHS ester structure
 Common Name Cyclooctyne-O-amido-PEG2-NHS ester
CAS Number 2101206-22-6 Molecular Weight 438.47
Density N/A Boiling Point N/A
Molecular Formula C21H30N2O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cyclooctyne-O-amido-PEG2-NHS ester


Cyclooctyne-O-amido-PEG2-NHS ester is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name Cyclooctyne-O-amido-PEG2-NHS ester

 Cyclooctyne-O-amido-PEG2-NHS ester Biological Activity

Description Cyclooctyne-O-amido-PEG2-NHS ester is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Non-cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

 Chemical & Physical Properties

Molecular Formula C21H30N2O8
Molecular Weight 438.47
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