PROTAC Linker 9

Modify Date: 2024-01-06 13:31:25

PROTAC Linker 9 Structure
PROTAC Linker 9 structure
Common Name PROTAC Linker 9
CAS Number 206265-94-3 Molecular Weight 403.49000
Density N/A Boiling Point N/A
Molecular Formula C18H29NO7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PROTAC Linker 9


PROTAC Linker 9 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 9 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

 Names

Name 2,2-dimethyl-4-oxo-3,8,11-trioxa-5-azatridecan-13-yl 4-methylbenzenesulfonate
Synonym More Synonyms

 PROTAC Linker 9 Biological Activity

Description PROTAC Linker 9 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 9 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog
Target

Alkyl/ether

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C18H29NO7S
Molecular Weight 403.49000
Exact Mass 403.16600
PSA 108.54000
LogP 3.72990

 Synonyms

t-Butyl-N-(2-{2-[2-(tosyloxy)-ethoxy]-ethoxy}-ethyl)-carbamate