NF-κB Control
NF-κB Control structure
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Common Name | NF-κB Control | ||
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| CAS Number | 201608-17-5 | Molecular Weight | 2668.33 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C123H215N33O30S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NF-κB ControlNF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. It blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α. NF-κB control is a peptide that is identical in sequence to NF-κB inhibitor, except two essential, basic residues of the p105 NLS are substituted with non-basic amino acids. It is ineffective at blocking the activation of NF-κB signaling and is used as a negative control peptide. |
| Name | NF-κB Control |
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| Description | NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. It blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α. NF-κB control is a peptide that is identical in sequence to NF-κB inhibitor, except two essential, basic residues of the p105 NLS are substituted with non-basic amino acids. It is ineffective at blocking the activation of NF-κB signaling and is used as a negative control peptide. |
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| Molecular Formula | C123H215N33O30S |
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| Molecular Weight | 2668.33 |