ER-27319
Modify Date: 2024-01-11 21:43:30
ER-27319 structure
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Common Name | ER-27319 | ||
|---|---|---|---|---|
| CAS Number | 201010-95-9 | Molecular Weight | 370.40 | |
| Density | 1.149g/cm3 | Boiling Point | 475.894ºC at 760 mmHg | |
| Molecular Formula | C20H22N2O5 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 241.613ºC | |
Use of ER-27319ER-27319, an acridone derivative, is a potent and selective SYK inhibitor, and inhibits the tyrosine phosphorylation of SYK and its activity. ER-27319 inhibits the release of antigen-induced allergic mediators from human and rat mast cells with an IC50 of 10 μM and can be used for study in allergic diseases[1][2]. |
| Name | 3,4-Dimethyl-10-(3-aminopropyl)-9-acridone oxalate |
|---|---|
| Synonym | More Synonyms |
| Description | ER-27319, an acridone derivative, is a potent and selective SYK inhibitor, and inhibits the tyrosine phosphorylation of SYK and its activity. ER-27319 inhibits the release of antigen-induced allergic mediators from human and rat mast cells with an IC50 of 10 μM and can be used for study in allergic diseases[1][2]. |
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| Related Catalog | |
| Target |
10 μM (Syk) in human and rat mast cells[1] |
| References |
| Density | 1.149g/cm3 |
|---|---|
| Boiling Point | 475.894ºC at 760 mmHg |
| Molecular Formula | C20H22N2O5 |
| Molecular Weight | 370.40 |
| Flash Point | 241.613ºC |
| Exact Mass | 396.16900 |
| PSA | 122.62000 |
| LogP | 3.53240 |
| Vapour Pressure | 0mmHg at 25°C |
| Index of Refraction | 1.611 |
| 3,4-Hexanediol,3,4-dimethyl-1,6-diphenyl |
| 3,4-dimethyl-1,6-diphenyl-3,4-hexanediol |