BCR-ABL-IN-1

Modify Date: 2024-01-17 15:19:59

BCR-ABL-IN-1 structure	Common Name	BCR-ABL-IN-1
	CAS Number	188260-50-6	Molecular Weight	459.44
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₁F₄N₅O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of BCR-ABL-IN-1

BCR-ABL-IN-1 is an inhibitor of BCR-ABL tyrosine kinase, with a pIC50 of 6.46, and may be used in the research of chronic myelogenous leukemia.

Name	BCR-ABL-IN-1

Description	BCR-ABL-IN-1 is an inhibitor of BCR-ABL tyrosine kinase, with a pIC50 of 6.46, and may be used in the research of chronic myelogenous leukemia.
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Bcr-Abl Research Areas >> Cancer
Target	pIC50: 6.46 (BCR-ABL)[1]
In Vitro	BCR-ABL-IN-1 (Compound 21) is an inhibitor of BCR-ABL tyrosine kinase, with a pIC50 of 6.46, and may be used in the research of chronic myelogenous leukemia.
References	[1]. Cui J1, et al. BCR-ABL tyrosine kinase inhibitor pharmacophore model derived from a series of phenylaminopyrimidine-based (PAP) derivatives. Bioorg Med Chem Lett. 2013 Apr 15;23(8):2442-50.

Molecular Formula	C₂₃H₂₁F₄N₅O
Molecular Weight	459.44
Storage condition	2-8℃