Diethyl succinate-13C4

Modify Date: 2024-01-30 18:22:20

Diethyl succinate-13C4 Structure
Diethyl succinate-13C4 structure
Common Name Diethyl succinate-13C4
CAS Number 1628796-56-4 Molecular Weight 178.16
Density N/A Boiling Point N/A
Molecular Formula C413C4H14O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Diethyl succinate-13C4


Diethyl succinate-13C4 is the 13C labeled Diethyl succinate[1]. Diethyl succinate (Diethyl Butanedioate) is used at physiological pH and crosses biological membranes, incorporates into cells in tissue culture and is metabolized by the TCA cycle. Diethyl succinate is known to be non-toxic and used in fragrances and flavoring[2].

 Names

Name Diethyl succinate-13C4

 Diethyl succinate-13C4 Biological Activity

Description Diethyl succinate-13C4 is the 13C labeled Diethyl succinate[1]. Diethyl succinate (Diethyl Butanedioate) is used at physiological pH and crosses biological membranes, incorporates into cells in tissue culture and is metabolized by the TCA cycle. Diethyl succinate is known to be non-toxic and used in fragrances and flavoring[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Zacharias NM, et al. Real-time molecular imaging of tricarboxylic acid cycle metabolism in vivo by hyperpolarized 1-(13)C diethyl succinate. J Am Chem Soc. 2012 Jan 18;134(2):934-43.  

 Chemical & Physical Properties

Molecular Formula C413C4H14O4
Molecular Weight 178.16