CCTA-1523

Modify Date: 2024-01-31 18:13:24

Use of CCTA-1523

CCTA-1523 is a potent, selective, reversible and orally active ABCG2 inhibitor. CCTA-1523 shows cytotoxicity. CCTA-1523 shows anticancer activity[1].

Name	Acetamide, 2,2-dichloro-N-(3',4'-dimethoxy[1,1'-biphenyl]-3-yl)-

Description	CCTA-1523 is a potent, selective, reversible and orally active ABCG2 inhibitor. CCTA-1523 shows cytotoxicity. CCTA-1523 shows anticancer activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Membrane Transporter/Ion Channel >> BCRP
References	[1]. Patel A,et al. Suppression of ABCG2 mediated MDR in vitro and in vivo by a novel inhibitor of ABCG2 drug transport. Pharmacol Res. 2017 Jul;121:184-193.

Molecular Formula	C₁₆H₁₅Cl₂NO₃
Molecular Weight	340.20