Nec-3a
Modify Date: 2025-08-26 00:24:56
Nec-3a structure
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Common Name | Nec-3a | ||
|---|---|---|---|---|
| CAS Number | 1504558-72-8 | Molecular Weight | 438.37 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H18F4N2O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Nec-3aNec-3a is a Necrostatin-3 analogue. Nec-3a is a RIP1 inhibitor (IC50: 0.44 μM). Nec-3a inhibits the autophosphorylation activity of the RIP1 kinase domain[1]. |
| Name | Nec-3a |
|---|
| Description | Nec-3a is a Necrostatin-3 analogue. Nec-3a is a RIP1 inhibitor (IC50: 0.44 μM). Nec-3a inhibits the autophosphorylation activity of the RIP1 kinase domain[1]. |
|---|---|
| Related Catalog | |
| Target |
RIPK1:0.44 μM (IC50) |
| References |
| Molecular Formula | C21H18F4N2O4 |
|---|---|
| Molecular Weight | 438.37 |
| InChIKey | RPGVJSZQQKMKSB-JLTOFOAXSA-N |
| SMILES | COc1ccc2c(c1)C1=NN(C(=O)CO)C(c3ccc(OC(F)(F)F)c(F)c3)C1CC2 |