Creatine-d3

Modify Date: 2024-01-07 07:19:20

Creatine-d3 Structure
Creatine-d3 structure
Common Name Creatine-d3
CAS Number 143827-19-4 Molecular Weight 134.15
Density N/A Boiling Point N/A
Molecular Formula C4H6D3N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Creatine-d3


Creatine-d3 is the deuterium labeled Creatine[1]. Creatine, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain[2].

 Names

Name Creatine-d3

 Creatine-d3 Biological Activity

Description Creatine-d3 is the deuterium labeled Creatine[1]. Creatine, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain[2].
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Nouioua S, et al. Creatine deficiency syndrome. A treatable myopathy due to arginine-glycine amidinotransferase (AGAT) deficiency. Neuromuscul Disord. 2013 Aug;23(8):670-4.  

 Chemical & Physical Properties

Molecular Formula C4H6D3N3O2
Molecular Weight 134.15