Glutathione arsenoxide

Modify Date: 2024-01-21 17:22:56

Glutathione arsenoxide Structure
Glutathione arsenoxide structure
Common Name Glutathione arsenoxide
CAS Number 1271726-51-2 Molecular Weight 548.40
Density N/A Boiling Point N/A
Molecular Formula C18H25AsN4O9S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Glutathione arsenoxide


Glutathione arsenoxide (GSAO) is a potential anticancer agent and a tumour metabolism inhibitor. Glutathione arsenoxide targets Mitochondrial endomycin nucleotide transferase (ANT). Glutathione arsenoxide causes cell proliferation arrest and cell death. Glutathione arsenoxide can be used to identify cell-surface proteins, such as Protein disulphide isomerase[1].

 Names

Name Glutathione arsenoxide

 Glutathione arsenoxide Biological Activity

Description Glutathione arsenoxide (GSAO) is a potential anticancer agent and a tumour metabolism inhibitor. Glutathione arsenoxide targets Mitochondrial endomycin nucleotide transferase (ANT). Glutathione arsenoxide causes cell proliferation arrest and cell death. Glutathione arsenoxide can be used to identify cell-surface proteins, such as Protein disulphide isomerase[1].
Related Catalog
Target

Mitochondrial endomycin nucleotide transferase (ANT), Protein disulphide isomerase (PDI)[1]

References

[1]. Park D, et al. The tumour metabolism inhibitors GSAO and PENAO react with cysteines 57 and 257 of mitochondrial adenine nucleotide translocase. Cancer Cell Int. 2012 Mar 26;12(1):11.  

[2]. Habeck M. Australian scientists design novel antiangiogenic weapon[J]. The Lancet Oncology, 2000, 1(4): 199.

 Chemical & Physical Properties

Molecular Formula C18H25AsN4O9S
Molecular Weight 548.40