Guaiacol-d7

Modify Date: 2024-01-20 11:30:55

Guaiacol-d7 structure	Common Name	Guaiacol-d7
	CAS Number	1065473-05-3	Molecular Weight	131.180
	Density	1.1±0.1 g/cm3	Boiling Point	205.0±0.0 °C at 760 mmHg
	Molecular Formula	C₇HD₇O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	82.2±0.0 °C

Use of Guaiacol-d7

Guaiacol-d7 is the deuterium labeled Guaiacol[1]. Guaiacol, a phenolic compound, inhibits LPS-stimulated COX-2 expression and NF-κB activation[1]. Anti-inflammatory activity[2].

Name	2-[(2H3)Methyloxy](2H4)phenol
Synonym	More Synonyms

Description	Guaiacol-d7 is the deuterium labeled Guaiacol[1]. Guaiacol, a phenolic compound, inhibits LPS-stimulated COX-2 expression and NF-κB activation[1]. Anti-inflammatory activity[2].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Murakami Y, et al. Re-evaluation of cyclooxygenase-2-inhibiting activity of vanillin and Guaiacol in macrophages stimulated with lipopolysaccharide. Anticancer Res. 2007 Mar-Apr;27(2):801-7.

Density	1.1±0.1 g/cm3
Boiling Point	205.0±0.0 °C at 760 mmHg
Molecular Formula	C₇HD₇O₂
Molecular Weight	131.180
Flash Point	82.2±0.0 °C
Exact Mass	131.096375
LogP	1.19
Vapour Pressure	0.2±0.4 mmHg at 25°C
Index of Refraction	1.535
Storage condition	2-8°C

2-[(H)Methyloxy](H)phenol

Phenol-2,3,4,5-d, 6-(methyl-d-oxy)-

Guaiacol-d7

Use of Guaiacol-d7

Names

Guaiacol-d7 Biological Activity

Chemical & Physical Properties

Synonyms