Palmitoyl Pentapeptide-4 (Matrixyl)

Published date: 2026-05-22 11:42:05

Palmitoyl Pentapeptide-4 (Matrixyl) Structure
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Name Palmitoyl pentapeptide-4 CAS# 214047-00-4
Price $53.42/100mg Purity 98.81%
Stocking
Period
3 Day Stock In Stock
Product Webpage: http://www.zhaokebio.com
 Detail Product Information
Palmitoyl Pentapeptide-4, widely known by the trade name Matrixyl, is a pioneering lipophilic signal peptide that revolutionized the anti-aging cosmetic industry. Developed by Sederma (France), it was the first peptide to demonstrate clinically significant wrinkle reduction comparable to retinoids, but without the associated irritation and photosensitivity. Matrixyl has become one of the most extensively studied and widely used anti-aging peptide ingredients in premium skincare formulations worldwide, with a robust body of clinical evidence supporting its efficacy.
The peptide sequence Lys-Thr-Thr-Lys-Ser (KTTKS) is a fragment of type I collagen (pro-collagen alpha-1 chain) conjugated with palmitic acid at the N-terminus. This pentapeptide mimics the natural signal that occurs when collagen breaks down in the skin, tricking the body into thinking that collagen degradation has occurred and triggering a wound-healing response. This signal activates fibroblasts to synthesize new collagen type I and III, elastin, and fibronectin, thereby replenishing the extracellular matrix and reducing the appearance of wrinkles from within.
Clinical studies have delivered impressive results: a landmark study with 3% Matrixyl showed a 68% reduction in wrinkle depth after 56 days of twice-daily application. A separate study demonstrated that Matrixyl reduced wrinkle surface by 44% and wrinkle density by 37%. As a specialized API sourcing partner, Shenzhen Zhaoke Biotechnology Co., Ltd. provides high-purity Palmitoyl Pentapeptide-4 (CAS No.: 214047-00-4) with comprehensive analytical documentation for global cosmetic and pharmaceutical manufacturers.

Supplier/Manufacture

Shenzhen Zhaoke Biotechnology Co., Ltd.

Chemsrc Level: Unverified
Tel: 0086-19842673490
Address: Room A207-208, Building A, No.3 Branch Park, Leibo Zhongcheng Life Science Park, Pingshan District, Shenzhen, Guangdong, China, 518118
Area: China
Contact: Jade Cheung
Contact Phone #: 19842673490
Email: jade.cheung@zhaokebio.com
Website: http://www.zhaokebio.com
Major Market: North America, Western Europe, Midde East, South Asia
Annual Trade Volume: 10,000,000
Foreign Trade % of Sales: 100%
Major partners:
Shenzhen Zhaoke Biotechnology Co., Ltd. operates as a specialized global procurement and supply chain solutions provider focused exclusively on high-quality peptide APIs. Rather than manufacturing, our core competency lies in strategically sourcing, rigorously vetting, and reliably delivering premium peptide products from qualified suppliers across the global pharmaceutical landscape.
We serve as the critical link between world-class peptide producers and pharmaceutical R&D enters, research institutions, and manufacturing enterprises across North America, Europe, Asia Pacific, and emerging markets. Our mission is to eliminate procurement complexity, mitigate supply risk, and ensure uncompromising quality at every stage of the sourcing journey.
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