| Name | Palmitoyl pentapeptide-4 | CAS# | 214047-00-4 | |
|---|---|---|---|---|
| Price | $53.42/100mg | Purity | 98.81% | |
| Stocking Period |
3 Day | Stock | In Stock | |
| Product Webpage: | http://www.zhaokebio.com | |||
| Detail
Product Information
Palmitoyl Pentapeptide-4, widely known by the trade name Matrixyl, is a pioneering lipophilic signal peptide that revolutionized the anti-aging cosmetic industry. Developed by Sederma (France), it was the first peptide to demonstrate clinically significant wrinkle reduction comparable to retinoids, but without the associated irritation and photosensitivity. Matrixyl has become one of the most extensively studied and widely used anti-aging peptide ingredients in premium skincare formulations worldwide, with a robust body of clinical evidence supporting its efficacy. The peptide sequence Lys-Thr-Thr-Lys-Ser (KTTKS) is a fragment of type I collagen (pro-collagen alpha-1 chain) conjugated with palmitic acid at the N-terminus. This pentapeptide mimics the natural signal that occurs when collagen breaks down in the skin, tricking the body into thinking that collagen degradation has occurred and triggering a wound-healing response. This signal activates fibroblasts to synthesize new collagen type I and III, elastin, and fibronectin, thereby replenishing the extracellular matrix and reducing the appearance of wrinkles from within. Clinical studies have delivered impressive results: a landmark study with 3% Matrixyl showed a 68% reduction in wrinkle depth after 56 days of twice-daily application. A separate study demonstrated that Matrixyl reduced wrinkle surface by 44% and wrinkle density by 37%. As a specialized API sourcing partner, Shenzhen Zhaoke Biotechnology Co., Ltd. provides high-purity Palmitoyl Pentapeptide-4 (CAS No.: 214047-00-4) with comprehensive analytical documentation for global cosmetic and pharmaceutical manufacturers. |