Acetyl Hexapeptide-8 (Argireline)
Published date: 2026-05-22 11:06:03
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Name | Argireline | CAS# | 616204-22-9 |
|---|---|---|---|---|
| Price | $83.87/100mg | Purity | 98.18% | |
| Stocking Period |
3 Day | Stock | In Stock | |
| Product Webpage: | http://www.zhaokebio.com | |||
| Detail
Product Information
Acetyl Hexapeptide-8, widely recognized by the trade name Argireline, is a synthetic cosmetic peptide and the world's first anti-wrinkle hexapeptide with a Botox-like mechanism of action. Developed by Lipotec (Barcelona, Spain) and first introduced to the cosmetic industry in 2002, it has since become one of the most extensively studied and widely used neuropeptides in premium skincare formulations globally. Its INCI name is Acetyl Hexapeptide-8, and it is also known as Acetyl Hexapeptide-3 in earlier literature. Acetyl Hexapeptide-8 is a six-amino-acid peptide with the sequence Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2, featuring an N-terminal acetyl group and a C-terminal amidation. These structural modifications enhance enzymatic stability and skin penetration. The peptide functions by mimicking the N-terminal region of the SNAP-25 protein, a critical component of the SNARE complex that mediates vesicle fusion and neurotransmitter release at neuromuscular junctions. By competitively binding within the SNARE complex, it destabilizes the assembly required for acetylcholine release, thereby reducing facial muscle contractions that cause dynamic expression wrinkles. Landmark clinical research published in the International Journal of Cosmetic Science (Blanes-Mira et al., 2002) demonstrated that a cream containing 10% Acetyl Hexapeptide-8 applied twice daily reduced wrinkle depth by up to 30% over 30 days, with significant improvements observed in the forehead and periocular areas. Unlike botulinum toxin, which requires injection and carries a risk of facial paralysis, Acetyl Hexapeptide-8 offers a safe, non-invasive topical alternative with a toxic potential approximately 4,000 times lower. As a specialized API sourcing partner, Shenzhen Zhaoke Biotechnology Co., Ltd. provides high-purity Acetyl Hexapeptide-8 (CAS No.: 616204-22-9) with comprehensive analytical documentation for global cosmetic and pharmaceutical manufacturers. Key Selling Points: Botox-Like Effect:SNAP-25 mimetic; reduces wrinkle depth by up to 30% in 30 days (10% cream, bid); Proven clinical efficacy; non-invasive topical alternative to injections 4,000x Safer:Toxic potential ~4,000 times lower than botulinum toxin; no paralysis risk; Safe for daily cosmetic use without medical supervision Enhanced Stability: N-acetyl and C-amide modifications improve enzymatic resistance and penetration; Superior shelf stability and effective skin delivery 20+ Year Track Record: Introduced 2002; most extensively studied neuropeptide in skincare; Well-established safety and efficacy profile globally INCI Listed: Official INCI name: Acetyl Hexapeptide-8; globally recognized; Easy regulatory approval in all major cosmetic markets One-Stop Procurement: Consolidated sourcing for cosmetic neuropeptides and active ingredients; Reduces supplier management complexity and cost |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Argireline
- Price: Check
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: Acetyl Hexapeptide-8
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
- Email: info@tianfuchem.com
- Zhongshan Xingrui Chemical Co. , Ltd.
- China
- Product Name: Argireline
- Price: ￥Inquiry/25kg
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Wang Jie
- Email: 3096638339@qq.com
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Price: $70/10mM*1mLinWater