velpatasvir
velpatasvir structure
|
Common Name | velpatasvir | ||
|---|---|---|---|---|
| CAS Number | 1377049-84-7 | Molecular Weight | 883.002 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C49H54N8O8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of velpatasvirVelpatasvir (VEL, GS-5816) is a novel pan-genotypic hepatitis C virus (HCV) nonstructural protein 5A (NS5A) inhibitor with activity against genotype 1 (GT1) to GT6 HCV replicons.target: NS5A |
Summary: Velpatasvir (VEL, CAS number: 1377049-84-7) is a novel NS5A inhibitor with molecular formula C49H54N8O8 and molecular weight 883.002. It appears as a powder with a density of 1.3±0.1 g/cm³ and should be stored at -20℃. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | Velpatasvir |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Velpatasvir (VEL, GS-5816) is a novel pan-genotypic hepatitis C virus (HCV) nonstructural protein 5A (NS5A) inhibitor with activity against genotype 1 (GT1) to GT6 HCV replicons.target: NS5A |
|---|---|
| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C49H54N8O8 |
| Molecular Weight | 883.002 |
| Exact Mass | 882.406433 |
| PSA | 193.10000 |
| LogP | 6.78 |
| Index of Refraction | 1.643 |
| Storage condition | -20℃ |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
|
Name: Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry
Source: NCGC
Target: N/A
External Id: TRND-SARS-CoV-2-cytotox-48hr
|
|
Name: Confirmatory qHTS to identify inhibitors of SARS-CoV-2 cell entry
Source: NCGC
External Id: TRND-SARS2-PP-HEK293ACE2-f4-mipe-npc
|
|
Name: VSVG counterscreen qHTS to identify inhibitors of SARS-CoV-2 cell entry
Source: NCGC
External Id: TRND-VSVG-PP-HEK293ACE2-f4-mipe-npc
|
|
Name: Primary qHTS to identify inhibitors of SARS-CoV-2 cell entry
Source: NCGC
External Id: TRND-SARS-CoV-2-PP
|
|
Name: Selectivity index, ratio of CC50 for human MRC5 cells infected with HCV genotype 1a H...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4386777
|
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| GS 5816 |
| velpatasvir |
| Methyl [(2S)-1-[(2S,5S)-2-[9-[2-[(2S,4S)-1-[(2R)-2-[(methoxycarbonyl)amino]-2-phenylacetyl]-4-(methoxymethyl)pyrrolidin-2-yl]-1H-imidazol-5-yl]-1,11-dihydroisochromeno[4',3':6,7]naphtho[1,2-d]imidazol-2-yl]-5-methylpyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate |
| Carbamic acid, N-[(1R)-2-[(2S,4S)-2-[4-[1,11-dihydro-2-[(2S,5S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methyl-1-oxobutyl]-5-methyl-2-pyrrolidinyl][2]benzopyrano[4',3':6,7]naphth[1,2-d]imidazol-9-yl]-1H-imidazol-2-yl]-4-(methoxymethyl)-1-pyrrolidinyl]-2-oxo-1-phenylethyl]-, methyl ester |
| Methyl {(2S)-1-[(2S,5S)-2-(9-{2-[(2S,4S)-1-{(2R)-2-[(methoxycarbonyl)amino]-2-phenylacetyl}-4-(methoxymethyl)-2-pyrrolidinyl]-1H-imidazol-4-yl}-1,11-dihydroisochromeno[4',3':6,7]naphtho[1,2-d]imidazol-2-yl)-5-methyl-1-pyrrolidinyl]-3-methyl-1-oxo-2-butanyl}carbamate |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the LogP of Velpatasvir? |
| A: LogP of Velpatasvir is 6.78. |
| Q: What is the English name of Velpatasvir? |
| A: The English name of Velpatasvir is Velpatasvir. |
| Q: What is the molecular weight of Velpatasvir? |
| A: Molecular weight of Velpatasvir is 883.002. |
| Q: What are the storage conditions for Velpatasvir? |
| A: Storage conditions for Velpatasvir: -20℃. |
| Q: What are the uses of Velpatasvir? |
| A: Main uses of Velpatasvir: Velpatasvir (VEL, GS-5816) is a novel pan-genotypic hepatitis C virus (HCV) nonstructural protein 5A (NS5A) inhibitor with activity against genotype 1 (GT1) to GT6 HCV replicons.target: NS5A. |
| Q: What is the CAS number of Velpatasvir? |
| A: CAS number of Velpatasvir is 1377049-84-7. |
| Q: What is the molecular formula of Velpatasvir? |
| A: Molecular formula of Velpatasvir is C49H54N8O8. |
| Q: What is the polar surface area (PSA) of Velpatasvir? |
| A: Polar surface area (PSA) of Velpatasvir is 193.10000. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Henan Tianfu Chemical Co., Ltd. |