2-(BIS-(2-PYRIDYLMETHYL)-AMINO)-ETHANOL structure
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Common Name | 2-(BIS-(2-PYRIDYLMETHYL)-AMINO)-ETHANOL | ||
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| CAS Number | 149860-22-0 | Molecular Weight | 243.30400 | |
| Density | 1.174g/cm3 | Boiling Point | 382ºC at 760 mmHg | |
| Molecular Formula | C14H17N3O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 184.8ºC | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 2-[bis(pyridin-2-ylmethyl)amino]ethanol |
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This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.174g/cm3 |
|---|---|
| Boiling Point | 382ºC at 760 mmHg |
| Molecular Formula | C14H17N3O |
| Molecular Weight | 243.30400 |
| Flash Point | 184.8ºC |
| Exact Mass | 243.13700 |
| PSA | 49.25000 |
| LogP | 1.47110 |
| Vapour Pressure | 1.62E-06mmHg at 25°C |
| Index of Refraction | 1.601 |
| InChIKey | DUFCPZLMEULRED-UHFFFAOYSA-N |
| SMILES | OCCN(Cc1ccccn1)Cc1ccccn1 |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
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Section1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE Product identifiers Product name: 2-(BIS-(2-PYRIDYLMETHYL)-AMINO)-ETHANOL CAS-No.: 149860-22-0 Section2. HAZARDS IDENTIFICATION
Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP] Skin irritation (Category 2) Serious eye damage (Category 1) Specific target organ toxicity - single exposure (Category 3) Classification according to EU Directives 67/548/EEC or 1999/45/EC Irritating to respiratory system and skin. Risk of serious damage to eyes. Label elements Labelling according Regulation (EC) No 1272/2008 [CLP] Pictogram Signal wordDanger Hazard statement(s) Causes skin irritation. Causes serious eye damage. May cause respiratory irritation. Precautionary statement(s) Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. Wear protective gloves/ eye protection/ face protection. P305 + P351 + P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Supplemental Hazardnone Statements According to European Directive 67/548/EEC as amended. Hazard symbol(s) R-phrase(s) R37/38Irritating to respiratory system and skin. R41Risk of serious damage to eyes. S-phrase(s) S26In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39Wear eye/face protection. Other hazards - none Section3. COMPOSITION/INFORMATION ON INGREDIENTS Substances Formula: C14H17N3O Molecular Weight: 243,31 g/mol ComponentConcentration 2-(BIS-(2-PYRIDYLMETHYL)-AMINO)-ETHANOL CAS-No.149860-22-0- Section4. FIRST AID MEASURES Description of first aid measures General advice Consult a physician. Show this safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. Most important symptoms and effects, both acute and delayed To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. Indication of any immediate medical attention and special treatment needed no data available Section5. FIRE-FIGHTING MEASURES Extinguishing media Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Special hazards arising from the substance or mixture Carbon oxides, nitrogen oxides (NOx) Advice for firefighters Wear self contained breathing apparatus for fire fighting if necessary. Further information no data available Section6. ACCIDENTAL RELEASE MEASURES Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. Environmental precautions Do not let product enter drains. Methods and materials for containment and cleaning up Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal. Reference to other sections For disposal see section 13. Section7. HANDLING AND STORAGE Precautions for safe handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Specific end uses no data available Section8. EXPOSURE CONTROLS/PERSONAL PROTECTION Control parameters Components with workplace control parameters Exposure controls Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Personal protective equipment Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Section9. PHYSICAL AND CHEMICAL PROPERTIES Information on basic physical and chemical properties a) AppearanceForm: solid b) Odourno data available c) Odour Thresholdno data available d) pHno data available e) Melting point/freezingno data available point f) Initial boiling point and no data available boiling range g) Flash pointno data available h) Evaporation rateno data available i) Flammability (solid, gas) no data available j) Upper/lowerno data available flammability or explosive limits k) Vapour pressureno data available l) Vapour densityno data available m) Relative densityno data available n) Water solubilityno data available o) Partition coefficient: n- log Pow: 0,636 octanol/water p) Autoignitionno data available temperature q) Decompositionno data available temperature r) Viscosityno data available s) Explosive propertiesno data available t) Oxidizing propertiesno data available Other safety information no data available Section10. STABILITY AND REACTIVITY Reactivity no data available Chemical stability no data available Possibility of hazardous reactions no data available Conditions to avoid no data available Incompatible materials Strong oxidizing agents Hazardous decomposition products Other decomposition products - no data available Section11. TOXICOLOGICAL INFORMATION Information on toxicological effects Acute toxicity no data available Skin corrosion/irritation no data available Serious eye damage/eye irritation no data available Respiratory or skin sensitization no data available Germ cell mutagenicity Carcinogenicity IARC:No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. Reproductive toxicity Specific target organ toxicity - single exposure May cause respiratory irritation. Specific target organ toxicity - repeated exposure no data available Aspiration hazard no data available Potential health effects InhalationMay be harmful if inhaled. Causes respiratory tract irritation. IngestionMay be harmful if swallowed. SkinMay be harmful if absorbed through skin. Causes skin irritation. EyesCauses eye burns. Signs and Symptoms of Exposure To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. Additional Information RTECS: Not available Section12. ECOLOGICAL INFORMATION Toxicity no data available Persistence and degradability no data available Bioaccumulative potential no data available Mobility in soil no data available Results of PBT and vPvB assessment no data available Other adverse effects no data available Section13. DISPOSAL CONSIDERATIONS Waste treatment methods Product Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Contaminated packaging Dispose of as unused product. Section14. TRANSPORT INFORMATION UN number ADR/RID: -IMDG: -IATA: - UN proper shipping name ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA:Not dangerous goods Transport hazard class(es) ADR/RID: -IMDG: -IATA: - Packaging group ADR/RID: -IMDG: -IATA: - Environmental hazards ADR/RID: noIMDG Marine pollutant: noIATA: no Special precautions for user no data available Section15. REGULATORY INFORMATION This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006. Safety, health and environmental regulations/legislation specific for the substance or mixture no data available Chemical Safety Assessment SECTION 16 - ADDITIONAL INFORMATION N/A |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~66%
2-(BIS-(2-PYRID... CAS#:149860-22-0 |
| Literature: INTERPROTEIN CORPORATION Patent: WO2009/84737 A1, 2009 ; Location in patent: Page/Page column 67-68 ; |
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~55%
2-(BIS-(2-PYRID... CAS#:149860-22-0 |
| Literature: INTERPROTEIN CORPORATION Patent: WO2009/84737 A1, 2009 ; Location in patent: Page/Page column 65-66 ; |
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~85%
2-(BIS-(2-PYRID... CAS#:149860-22-0 |
| Literature: Sundaravel, Karuppasamy; Sankaralingam, Muniyandi; Suresh, Eringathodi; Palaniandavar, Mallayan Dalton Transactions, 2011 , vol. 40, # 33 p. 8444 - 8458 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 4 | |
|---|---|
| DownStream 0 | |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: uHTS identification of microRNA-mediated mRNA deadenylation inhibitors by fluoresence...
Source: Burnham Center for Chemical Genomics
Target: polyadenylate-binding protein 1 [Homo sapiens]
External Id: SBCCG-A704-MLLE-PAM2-Inh-Primary-Assay
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Name: uHTS identification of small molecule modulators of myocardial damage
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: SBCCG-A705-H9c2-Inh-Primary-Assay
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Name: uHTS identification of inhibitors of Rpn11 in a Fluorescent Polarization assay
Source: Burnham Center for Chemical Genomics
Target: PSMD14 protein [Homo sapiens]
External Id: SBCCG-A706-Rpn11-Inh-Primary-Assay
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Name: uHTS identification of small molecule inhibitors of Striatal-Enriched Phosphatase via...
Source: Burnham Center for Chemical Genomics
Target: tyrosine-protein phosphatase non-receptor type 5 isoform a [Homo sapiens]
External Id: SBCCG-A754-STEP-Primary-Assay
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: Luminescence-based cell-based primary high throughput screening assay to identify inh...
Source: The Scripps Research Institute Molecular Screening Center
Target: nuclear receptor coactivator 3 isoform a [Homo sapiens]
External Id: SRC3_INH_LUMI_1536_1X%INH PRUN
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Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1100
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Name: qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primar...
Source: NCGC
Target: 67.9K protein [Vaccinia virus]
External Id: Vaccinia-p2mCherry
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Name: qHTS for Agonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): prim...
Source: NCGC
Target: RecName: Full=Rap guanine nucleotide exchange factor 3; AltName: Full=Exchange factor directly activated by cAMP 1; AltName: Full=Exchange protein directly activated by cAMP 1; Short=EPAC 1; AltName: Full=Rap1 guanine-nucleotide-exchange factor directly activated by cAMP; AltName: Full=cAMP-regulated guanine nucleotide exchange factor I; Short=cAMP-GEFI
External Id: EPAC1-agonist-p1
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Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1101
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This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the polar surface area (PSA) of 2-[bis(pyridin-2-ylmethyl)amino]ethanol? |
| A: Polar surface area (PSA) of 2-[bis(pyridin-2-ylmethyl)amino]ethanol is 49.25000. |
| Q: What is the English name of 2-[bis(pyridin-2-ylmethyl)amino]ethanol? |
| A: The English name of 2-[bis(pyridin-2-ylmethyl)amino]ethanol is 2-[bis(pyridin-2-ylmethyl)amino]ethanol. |
| Q: What is the InChIKey of 2-[bis(pyridin-2-ylmethyl)amino]ethanol? |
| A: InChIKey of 2-[bis(pyridin-2-ylmethyl)amino]ethanol is DUFCPZLMEULRED-UHFFFAOYSA-N. |
| Q: What are the upstream materials of 2-[bis(pyridin-2-ylmethyl)amino]ethanol? |
| A: Related upstream materials(CAS) of 2-[bis(pyridin-2-ylmethyl)amino]ethanol: 6959-47-3;141-43-5;4377-33-7;1121-60-4. |
| Q: What is the CAS number of 2-[bis(pyridin-2-ylmethyl)amino]ethanol? |
| A: CAS number of 2-[bis(pyridin-2-ylmethyl)amino]ethanol is 149860-22-0. |
| Q: What is the boiling point of 2-[bis(pyridin-2-ylmethyl)amino]ethanol? |
| A: Boiling point of 2-[bis(pyridin-2-ylmethyl)amino]ethanol is 382ºC at 760 mmHg. |
| Q: What is the SMILES notation of 2-[bis(pyridin-2-ylmethyl)amino]ethanol? |
| A: SMILES notation of 2-[bis(pyridin-2-ylmethyl)amino]ethanol is OCCN(Cc1ccccn1)Cc1ccccn1. |
| Q: What is the molecular weight of 2-[bis(pyridin-2-ylmethyl)amino]ethanol? |
| A: Molecular weight of 2-[bis(pyridin-2-ylmethyl)amino]ethanol is 243.30400. |
| Q: What is the molecular formula of 2-[bis(pyridin-2-ylmethyl)amino]ethanol? |
| A: Molecular formula of 2-[bis(pyridin-2-ylmethyl)amino]ethanol is C14H17N3O. |
| Q: What is the LogP of 2-[bis(pyridin-2-ylmethyl)amino]ethanol? |
| A: LogP of 2-[bis(pyridin-2-ylmethyl)amino]ethanol is 1.47110. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |