[1-[(Boc-amino)methyl]cyclopropyl]methanol
![[1-[(Boc-amino)methyl]cyclopropyl]methanol Structure](https://image.chemsrc.com/caspic/416/153248-46-5.png)
[1-[(Boc-amino)methyl]cyclopropyl]methanol structure
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Common Name | [1-[(Boc-amino)methyl]cyclopropyl]methanol | ||
|---|---|---|---|---|
| CAS Number | 153248-46-5 | Molecular Weight | 201.263 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 311.3±15.0 °C at 760 mmHg | |
| Molecular Formula | C10H19NO3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 142.0±20.4 °C | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | tert-butyl N-[[1-(hydroxymethyl)cyclopropyl]methyl]carbamate |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 311.3±15.0 °C at 760 mmHg |
| Molecular Formula | C10H19NO3 |
| Molecular Weight | 201.263 |
| Flash Point | 142.0±20.4 °C |
| Exact Mass | 201.136490 |
| PSA | 62.05000 |
| LogP | 0.85 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.483 |
| InChIKey | NQILLQJICWRVRV-UHFFFAOYSA-N |
| SMILES | CC(C)(C)OC(=O)NCC1(CO)CC1 |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| HS Code | 2924299090 |
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This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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[1-[(Boc-amino)... CAS#:153248-46-5 |
| Literature: Buchholz, Mirko; Heiser, Ulrich; Schilling, Stephan; Niestroj, Andre J.; Zunkel, Katrin; Demuth, Hans-Ulrich Journal of Medicinal Chemistry, 2006 , vol. 49, # 2 p. 664 - 677 |
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[1-[(Boc-amino)... CAS#:153248-46-5 |
| Literature: LEO Pharma A/S; NIELSEN, Simon Feldbaek; VIFIAN, Thomas; HORNEMAN, Anne Marie; LAU, Jesper Faergemann Patent: WO2010/69322 A1, 2010 ; Location in patent: Page/Page column 58 ; |
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[1-[(Boc-amino)... CAS#:153248-46-5 |
| Literature: Buchholz, Mirko; Heiser, Ulrich; Schilling, Stephan; Niestroj, Andre J.; Zunkel, Katrin; Demuth, Hans-Ulrich Journal of Medicinal Chemistry, 2006 , vol. 49, # 2 p. 664 - 677 |
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[1-[(Boc-amino)... CAS#:153248-46-5 |
| Literature: BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOYER, Stephen, James; GAO, Donghong, Amy; GUO, Xin; KIRRANE, Thomas, Martin, Jr.; SARKO, Christopher, Ronald; SNOW, Roger, John; SOLEYMANZADEH, Fariba; ZHANG, Yunlong Patent: WO2011/71716 A1, 2011 ; WO 2011/071716 A1 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 5 | |
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| DownStream 1 | |
CAS#:877204-21-2This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2924299090 |
|---|---|
| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Primary screen in NF54 nanoGlo assay, in single point, at 2uM, 72h
Source: ChEMBL
Target: Plasmodium falciparum
External Id: CHEMBL4888485
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| (1-Hydroxymethyl-cyclopropylmethyl); -carbamic acid tert-butyl ester |
| (N-Boc-1-aminomethyl-cycIopropyl)-methanol |
| Carbamic acid, N-[[1-(hydroxymethyl)cyclopropyl]methyl]-, 1,1-dimethylethyl ester |
| tert-butyl (1-(hydroxymethyl)cyclo-1-propyl)methylcarbamate |
| 1,1-dimethylethyl {[1-(hydroxymethyl)cyclopropyl]methyl}carbamate |
| tert-Butyl ((1-(hydroxymethyl)cyclopropyl)methyl)carbamate |
| N-tert-butoxycarbonyl-1-aminomethyl-1-cyclopropylmethanol |
| (1-Hydroxymethyl-cyclopropylmethyl)-carbamic acid tert-butyl ester |
| tert-Butyl {[1-(hydroxymethyl)cyclopropyl]methyl}carbamate |
| 2-Methyl-2-propanyl {[1-(hydroxymethyl)cyclopropyl]methyl}carbamate |
| 1-Hydroxymethyl-1-(Boc-aminomethyl)cyclopropane |
| TERT-BUTYL N-([1-(HYDROXYMETHYL)CYCLOPROPYL]METHYL)CARBAMATE |
| N-Boc-1-aminomethyl-cyclopropyl-methanol |
| [1-[(Boc-amino)methyl]cyclopropyl]methanol |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the CAS number of tert-butyl N-[[1-(hydroxymethyl)cyclopropyl]methyl]carbamate? |
| A: CAS number of tert-butyl N-[[1-(hydroxymethyl)cyclopropyl]methyl]carbamate is 153248-46-5. |
| Q: What is the boiling point of tert-butyl N-[[1-(hydroxymethyl)cyclopropyl]methyl]carbamate? |
| A: Boiling point of tert-butyl N-[[1-(hydroxymethyl)cyclopropyl]methyl]carbamate is 311.3±15.0 °C at 760 mmHg. |
| Q: What is the polar surface area (PSA) of tert-butyl N-[[1-(hydroxymethyl)cyclopropyl]methyl]carbamate? |
| A: Polar surface area (PSA) of tert-butyl N-[[1-(hydroxymethyl)cyclopropyl]methyl]carbamate is 62.05000. |
| Q: What are the upstream materials of tert-butyl N-[[1-(hydroxymethyl)cyclopropyl]methyl]carbamate? |
| A: Related upstream materials(CAS) of tert-butyl N-[[1-(hydroxymethyl)cyclopropyl]methyl]carbamate: 24424-99-5;45434-02-4;204376-48-7;6914-80-3;3697-69-6. |
| Q: What is the InChIKey of tert-butyl N-[[1-(hydroxymethyl)cyclopropyl]methyl]carbamate? |
| A: InChIKey of tert-butyl N-[[1-(hydroxymethyl)cyclopropyl]methyl]carbamate is NQILLQJICWRVRV-UHFFFAOYSA-N. |
| Q: What is the LogP of tert-butyl N-[[1-(hydroxymethyl)cyclopropyl]methyl]carbamate? |
| A: LogP of tert-butyl N-[[1-(hydroxymethyl)cyclopropyl]methyl]carbamate is 0.85. |
| Q: What is the English name of tert-butyl N-[[1-(hydroxymethyl)cyclopropyl]methyl]carbamate? |
| A: The English name of tert-butyl N-[[1-(hydroxymethyl)cyclopropyl]methyl]carbamate is tert-butyl N-[[1-(hydroxymethyl)cyclopropyl]methyl]carbamate. |
| Q: What are the downstream products of tert-butyl N-[[1-(hydroxymethyl)cyclopropyl]methyl]carbamate? |
| A: Related downstream products(CAS) of tert-butyl N-[[1-(hydroxymethyl)cyclopropyl]methyl]carbamate: 877204-21-2. |
| Q: What is the SMILES notation of tert-butyl N-[[1-(hydroxymethyl)cyclopropyl]methyl]carbamate? |
| A: SMILES notation of tert-butyl N-[[1-(hydroxymethyl)cyclopropyl]methyl]carbamate is CC(C)(C)OC(=O)NCC1(CO)CC1. |
| Q: What is the molecular weight of tert-butyl N-[[1-(hydroxymethyl)cyclopropyl]methyl]carbamate? |
| A: Molecular weight of tert-butyl N-[[1-(hydroxymethyl)cyclopropyl]methyl]carbamate is 201.263. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |