Beta-d-N4-hydroxycytidine structure
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Common Name | Beta-d-N4-hydroxycytidine | ||
|---|---|---|---|---|
| CAS Number | 3258-02-4 | Molecular Weight | 259.21600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C9H13N3O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Beta-d-N4-hydroxycytidineBeta-d-N4-hydroxycytidine is a very potent anti-VEEV (venezuelan equine encephalitis virus) agent with EC50, EC90, and EC99 are 0.426, 1.036, and 2.5 μM, respectively[1]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Beta-d-N4-hydroxycytidine is a very potent anti-VEEV (venezuelan equine encephalitis virus) agent with EC50, EC90, and EC99 are 0.426, 1.036, and 2.5 μM, respectively[1]. |
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| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C9H13N3O6 |
|---|---|
| Molecular Weight | 259.21600 |
| Exact Mass | 259.08000 |
| PSA | 137.07000 |
| InChIKey | XCUAIINAJCDIPM-XVFCMESISA-N |
| SMILES | O=c1nc(NO)ccn1C1OC(CO)C(O)C1O |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 0 | |
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| DownStream 1 | |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Antiviral activity against wild type SARS CoV-2 infected in Vero E6 cells transfected...
Source: ChEMBL
Target: Severe acute respiratory syndrome coronavirus 2
External Id: CHEMBL5112762
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Name: Antiviral activity against wild type SARS CoV-2 infected in Vero E6 cells transfected...
Source: ChEMBL
Target: Severe acute respiratory syndrome coronavirus 2
External Id: CHEMBL5112763
|
|
Name: Cytotoxicity against African green monkey Vero E6 cells transfected with TMPRSS2 asse...
Source: ChEMBL
Target: Vero C1008
External Id: CHEMBL5112764
|
|
Name: Antiviral activity against SARS CoV infected in HEK293T cells transfected with ACE2 a...
Source: ChEMBL
Target: Severe acute respiratory syndrome-related coronavirus
External Id: CHEMBL5112765
|
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Name: Antiviral activity against SARS CoV-2 delta TY11-927 infected in HEK293T cells transf...
Source: ChEMBL
Target: Severe acute respiratory syndrome coronavirus 2
External Id: CHEMBL5112758
|
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Name: Half life in CD1 mouse at 150 mg/kg, po administered as single dose by LC-MS/MS analy...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5137627
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|
Name: Antiviral activity against SARS CoV-2 omicron TY38-873 BA.1 variant infected in HEK29...
Source: ChEMBL
Target: Severe acute respiratory syndrome coronavirus 2
External Id: CHEMBL5112759
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|
Name: Half life in CD1 mouse at 500 mg/kg, po administered as single dose by LC-MS/MS analy...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5137628
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|
Name: Antiviral activity against SARS CoV-2 omicron TY38-873 BA.2 variant infected in HEK29...
Source: ChEMBL
Target: Severe acute respiratory syndrome coronavirus 2
External Id: CHEMBL5112760
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|
Name: Substrate activity at human mARC1 expressed in Escherichia coli assessed as turnover ...
Source: ChEMBL
Target: Mitochondrial amidoxime-reducing component 1
External Id: CHEMBL4614164
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Uridine,4-oxime |
| N4-Hydroxycytidine |
| Cytidine,N-hydroxy |
| 4-N-Hydroxycytidine |
| EIDD-1931 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the Chinese name of 3258-02-4? |
| A: Chinese name of 3258-02-4 is Beta-d-N4-hydroxycytidine. |
| Q: What English synonyms does 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one have? |
| A: English synonyms of 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one: Uridine,4-oxime, N4-Hydroxycytidine, Cytidine,N-hydroxy, 4-N-Hydroxycytidine, EIDD-1931. |
| Q: What is the polar surface area (PSA) of 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one? |
| A: Polar surface area (PSA) of 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one is 137.07000. |
| Q: What is the CAS number of 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one? |
| A: CAS number of 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one is 3258-02-4. |
| Q: What is the molecular weight of 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one? |
| A: Molecular weight of 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one is 259.21600. |
| Q: What is the InChIKey of 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one? |
| A: InChIKey of 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one is XCUAIINAJCDIPM-XVFCMESISA-N. |
| Q: What is the molecular formula of 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one? |
| A: Molecular formula of 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one is C9H13N3O6. |
| Q: What are the downstream products of 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one? |
| A: Related downstream products(CAS) of 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one: 65-46-3. |
| Q: What are the uses of 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one? |
| A: Main uses of 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one: Beta-d-N4-hydroxycytidine is a very potent anti-VEEV (venezuelan equine encephalitis virus) agent with EC50, EC90, and EC99 are 0.426, 1.036, and 2.5 μM, respectively[1]. |
| Q: What is the English name of 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one? |
| A: The English name of 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one is 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Dayang Chem (Hangzhou) Co., Ltd. |
| Henan Tianfu Chemical Co., Ltd. |