1H-Benzimidazol-2-amine,N-butyl
1H-Benzimidazol-2-amine,N-butyl structure
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Common Name | 1H-Benzimidazol-2-amine,N-butyl | ||
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| CAS Number | 51314-51-3 | Molecular Weight | 189.26 | |
| Density | 1.153g/cm3 | Boiling Point | 344.8ºC at 760 mmHg | |
| Molecular Formula | C11H15N3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 162.3ºC | |
Use of 1H-Benzimidazol-2-amine,N-butylM084 is a benzimidazole derivative. M084 inhibits the mitochondrial respiration, activate mitochondrial unfolded protein response and AMPK, recruites SIR-2.1 and SKN-1, and finally through the transcription factor DAF-16, delays the aging process of C. elegans[1]. |
| Name | butyl(1,3-dihydrobenzimidazol-2-ylidene)azanium |
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| Synonym | More Synonyms |
| Description | M084 is a benzimidazole derivative. M084 inhibits the mitochondrial respiration, activate mitochondrial unfolded protein response and AMPK, recruites SIR-2.1 and SKN-1, and finally through the transcription factor DAF-16, delays the aging process of C. elegans[1]. |
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| Related Catalog | |
| References |
| Density | 1.153g/cm3 |
|---|---|
| Boiling Point | 344.8ºC at 760 mmHg |
| Molecular Formula | C11H15N3 |
| Molecular Weight | 189.26 |
| Flash Point | 162.3ºC |
| Exact Mass | 189.12700 |
| PSA | 40.71000 |
| LogP | 2.84790 |
| Index of Refraction | 1.653 |
| InChIKey | OKKUCNXCFWODOE-UHFFFAOYSA-N |
| SMILES | CCCCNc1nc2ccccc2[nH]1 |
| HS Code | 2933990090 |
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~57%
1H-Benzimidazol... CAS#:51314-51-3 |
| Literature: Linciano, Pasquale; Pizzetti, Marianna; Porcheddu, Andrea; Taddei, Maurizio Synlett, 2013 , vol. 24, # 17 p. 2249 - 2254 |
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~90%
1H-Benzimidazol... CAS#:51314-51-3 |
| Literature: Zhu, Jinmei; Wu, Chun-Feng; Li, Xiaobing; Wu, Gui-Sheng; Xie, Shan; Hu, Qian-Nan; Deng, Zixin; Zhu, Michael X.; Luo, Huai-Rong; Hong, Xuechuan Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 14 p. 4218 - 4224 |
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~95%
1H-Benzimidazol... CAS#:51314-51-3 |
| Literature: Li, Feng; Kang, Qikai; Shan, Haixia; Chen, Lin; Xie, Jianjiang European Journal of Organic Chemistry, 2012 , # 26 p. 5085 - 5092 |
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~71%
1H-Benzimidazol... CAS#:51314-51-3 |
| Literature: Zhu, Tong-Hao; Wang, Shun-Yi; Wang, Gao-Nan; Ji, Shun-Jun Chemistry - A European Journal, 2013 , vol. 19, # 19 p. 5850 - 5853 |
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~%
1H-Benzimidazol... CAS#:51314-51-3 |
| Literature: Barrett, Ian C.; Kerr, Michael A. Tetrahedron Letters, 1999 , vol. 40, # 13 p. 2439 - 2442 |
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~%
1H-Benzimidazol... CAS#:51314-51-3 |
| Literature: Tittelbach, Franz; Martin, Dieter Journal fuer Praktische Chemie (Leipzig), 1988 , vol. 330, # 3 p. 338 - 348 |
|
~%
1H-Benzimidazol... CAS#:51314-51-3 |
| Literature: Tittelbach, Franz; Martin, Dieter Journal fuer Praktische Chemie (Leipzig), 1988 , vol. 330, # 3 p. 338 - 348 |
|
~%
1H-Benzimidazol... CAS#:51314-51-3 |
| Literature: Tittelbach, Franz; Martin, Dieter Journal fuer Praktische Chemie (Leipzig), 1988 , vol. 330, # 3 p. 338 - 348 |
|
~%
1H-Benzimidazol... CAS#:51314-51-3 |
| Literature: Tittelbach, Franz; Martin, Dieter Journal fuer Praktische Chemie (Leipzig), 1988 , vol. 330, # 3 p. 338 - 348 |
![2-phenyl-2H-benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazol-3-one structure](https://image.chemsrc.com/caspic/251/72885-92-8.png)
![2-ethyl-1,2,4-thiadiazolo[4,5-a]benzimidazole-3(2H)-one structure](https://www.chemsrc.com/extcaspic/283/98154-63-3.png)
| Precursor 9 | |
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| DownStream 0 | |
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
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Name: Specificity screen against TRPC6 for compounds that activate transient receptor poten...
Source: Johns Hopkins Ion Channel Center
Target: short transient receptor potential channel 6 [Mus musculus]
External Id: TRPC4_AG_Counter_C6
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
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Name: Specificity screen against TRPC6 for compounds that inhibit transient receptor potent...
Source: Johns Hopkins Ion Channel Center
Target: short transient receptor potential channel 6 [Mus musculus]
External Id: TRPC4_Inh_Counter_C6
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|
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979
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Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
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Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
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| 2-N-butylamino-1H-benzimidazole |
| 2-n-Butylaminobenzimidazol |
| N-Butyl-1H-Benzimidazol-2-Amine |