6-NITROQUINOLIN-2(1H)-ONE

Modify Date: 2025-08-25 14:24:38

6-NITROQUINOLIN-2(1H)-ONE Structure
6-NITROQUINOLIN-2(1H)-ONE structure
Common Name 6-NITROQUINOLIN-2(1H)-ONE
CAS Number 64495-55-2 Molecular Weight 190.15600
Density N/A Boiling Point N/A
Molecular Formula C9H6N2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 6-nitro-1H-quinolin-2-one
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Molecular Formula C9H6N2O3
Molecular Weight 190.15600
Exact Mass 190.03800
PSA 78.68000
LogP 1.95950
InChIKey OYLJUJGLDPDXHP-UHFFFAOYSA-N
SMILES O=c1ccc2cc([N+](=O)[O-])ccc2[nH]1

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

Material Safety Data Sheet

Section1. Identification of the substance
Product Name: 6-Nitro-1H-quinolin-2-one
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.

Section3. Composition/information on ingredients.
Ingredient name:6-Nitro-1H-quinolin-2-one
CAS number:64495-55-2

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Store in closed vessels.
Storage:

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
No data
Melting point:
Flash point:No data
Density:No data
Molecular formula:C9H6N2O3
Molecular weight:190.2

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

HS Code 2933790090

 Precursor & DownStream

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor  0

DownStream  3

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2933790090
Summary 2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

 6-NITROQUINOLIN-2(1H)-ONEBioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Antileishmanial activity against Leishmania donovani MHOM/IN/00/DEVI promastigotes af...
Source: ChEMBL
Target: Leishmania donovani
External Id: CHEMBL2044348
Name: Electrochemical behavior of the compound assessed as redox potential corrected toward...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4155543
Name: Antileishmanial activity against axenic amastigote stage of Leishmania infantum MHOM/...
Source: ChEMBL
Target: Leishmania infantum
External Id: CHEMBL4155544
Name: Antitrypanosomal activity against trypomastigote stage of Trypanosoma brucei brucei A...
Source: ChEMBL
Target: Trypanosoma brucei brucei
External Id: CHEMBL4155545
Name: Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 7...
Source: ChEMBL
Target: HepG2
External Id: CHEMBL4155546
Name: Selectivity index, ratio of CC50 for mouse J774A1 cells to IC50 for Leishmania donova...
Source: ChEMBL
Target: N/A
External Id: CHEMBL2044355
Name: Cytotoxicity against mouse J774A1 cells after 72 hrs by MTT assay
Source: ChEMBL
Target: J774.A1
External Id: CHEMBL2044353
Name: Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
Source: ChEMBL
Target: HepG2
External Id: CHEMBL2044354
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1

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

6-Nitro-chinolin-2-ol
5-nitro-2-quinolone
6-nitro-quinolin-2-ol

 6-NITROQUINOLIN-2(1H)-ONE | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the polar surface area (PSA) of 6-nitro-1H-quinolin-2-one?
A: Polar surface area (PSA) of 6-nitro-1H-quinolin-2-one is 78.68000.
Q: What is the InChIKey of 6-nitro-1H-quinolin-2-one?
A: InChIKey of 6-nitro-1H-quinolin-2-one is OYLJUJGLDPDXHP-UHFFFAOYSA-N.
Q: What is the SMILES notation of 6-nitro-1H-quinolin-2-one?
A: SMILES notation of 6-nitro-1H-quinolin-2-one is O=c1ccc2cc([N+](=O)[O-])ccc2[nH]1.
Q: What is the molecular weight of 6-nitro-1H-quinolin-2-one?
A: Molecular weight of 6-nitro-1H-quinolin-2-one is 190.15600.
Q: What is the CAS number of 6-nitro-1H-quinolin-2-one?
A: CAS number of 6-nitro-1H-quinolin-2-one is 64495-55-2.
Q: What English synonyms does 6-nitro-1H-quinolin-2-one have?
A: English synonyms of 6-nitro-1H-quinolin-2-one: 6-Nitro-chinolin-2-ol, 5-nitro-2-quinolone, 6-nitro-quinolin-2-ol.
Q: What is the molecular formula of 6-nitro-1H-quinolin-2-one?
A: Molecular formula of 6-nitro-1H-quinolin-2-one is C9H6N2O3.
Q: What is the English name of 6-nitro-1H-quinolin-2-one?
A: The English name of 6-nitro-1H-quinolin-2-one is 6-nitro-1H-quinolin-2-one.
Q: What is the LogP of 6-nitro-1H-quinolin-2-one?
A: LogP of 6-nitro-1H-quinolin-2-one is 1.95950.
Q: What are the downstream products of 6-nitro-1H-quinolin-2-one?
A: Related downstream products(CAS) of 6-nitro-1H-quinolin-2-one: 296759-32-5;616-79-5;29969-57-1.

 6-NITROQUINOLIN-2(1H)-ONEfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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