7-Amino-1,2,3,4-tetrahydroisoquinoline
7-Amino-1,2,3,4-tetrahydroisoquinoline structure
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Common Name | 7-Amino-1,2,3,4-tetrahydroisoquinoline | ||
|---|---|---|---|---|
| CAS Number | 72299-68-4 | Molecular Weight | 148.205 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 315.9±42.0 °C at 760 mmHg | |
| Molecular Formula | C9H12N2 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 169.2±31.5 °C | |
Summary: 7-Amino-1,2,3,4-tetrahydroisoquinoline, Chinese name: 1,2,3,4-tetrahydroisoquinoline-7-amine, CAS number: 72299-68-4, molecular formula: C9H12N2, molecular weight: 148.205. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 7-Amino-1,2,3,4-tetrahydroisoquinoline |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 315.9±42.0 °C at 760 mmHg |
| Molecular Formula | C9H12N2 |
| Molecular Weight | 148.205 |
| Flash Point | 169.2±31.5 °C |
| Exact Mass | 148.100052 |
| PSA | 38.05000 |
| LogP | 0.12 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.600 |
| InChIKey | VMEDBFRQSKKEEQ-UHFFFAOYSA-N |
| SMILES | Nc1ccc2c(c1)CNCC2 |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| HS Code | 2933499090 |
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This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~90%
7-Amino-1,2,3,4... CAS#:72299-68-4 |
| Literature: Grunewald, Gary L.; Dahanukar, Vilas H.; Caldwell, Timothy M.; Criscione, Kevin R. Journal of Medicinal Chemistry, 1997 , vol. 40, # 25 p. 3997 - 4005 |
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~85%
7-Amino-1,2,3,4... CAS#:72299-68-4 |
| Literature: Butora, Gabor; Goble, Stephen D.; Pastemak, Alexander; Yang, Lihu; Zhou, Changyou; Moyes, Christopher R. Patent: US2008/81803 A1, 2008 ; Location in patent: Page/Page column 71 ; US 20080081803 A1 |
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7-Amino-1,2,3,4... CAS#:72299-68-4
Learn More
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| Literature: WO2009/62658 A1, ; Page/Page column 37 ; WO 2009/062658 A1 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 3 | |
|---|---|
| DownStream 5 | |
CAS#:17680-55-6
CAS#:885270-54-2
CAS#:149355-52-2
CAS#:171049-41-5
CAS#:81885-67-8This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933499090 |
|---|---|
| Summary | 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Inhibitory activity against bovine adrenal phenylethanolamine N-methyl-transferase (P...
Source: ChEMBL
Target: Phenylethanolamine N-methyltransferase
External Id: CHEMBL760054
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Name: Inhibition of [3H]clonidine binding to the rat alpha-2-adrenoceptor
Source: ChEMBL
Target: Alpha-2A adrenergic receptor
External Id: CHEMBL641405
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Name: In vitro inhibitory activity against bovine adrenal phenylethanolamine N-methyl-trans...
Source: ChEMBL
Target: Phenylethanolamine N-methyltransferase
External Id: CHEMBL764113
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Name: In vitro inhibitory activity against Alpha-2 adrenergic receptor using [3H]clonidine ...
Source: ChEMBL
Target: Alpha-2A adrenergic receptor
External Id: CHEMBL649642
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Name: Binding selectivity against PNMT and alpha-2-adrenoceptors, measured as a ratio of re...
Source: ChEMBL
Target: N/A
External Id: CHEMBL764118
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 1,2,3,4-Tetrahydro-7-isoquinolinamine |
| 1,2,3,4-Tetrahydroisoquinolin-7-amine |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the LogP of 7-Amino-1,2,3,4-tetrahydroisoquinoline? |
| A: LogP of 7-Amino-1,2,3,4-tetrahydroisoquinoline is 0.12. |
| Q: What is the molecular weight of 7-Amino-1,2,3,4-tetrahydroisoquinoline? |
| A: Molecular weight of 7-Amino-1,2,3,4-tetrahydroisoquinoline is 148.205. |
| Q: What is the boiling point of 7-Amino-1,2,3,4-tetrahydroisoquinoline? |
| A: Boiling point of 7-Amino-1,2,3,4-tetrahydroisoquinoline is 315.9±42.0 °C at 760 mmHg. |
| Q: What are the downstream products of 7-Amino-1,2,3,4-tetrahydroisoquinoline? |
| A: Related downstream products(CAS) of 7-Amino-1,2,3,4-tetrahydroisoquinoline: 17680-55-6;885270-54-2;149355-52-2;171049-41-5;81885-67-8. |
| Q: What are the upstream materials of 7-Amino-1,2,3,4-tetrahydroisoquinoline? |
| A: Related upstream materials(CAS) of 7-Amino-1,2,3,4-tetrahydroisoquinoline: 99365-69-2;42923-79-5;186390-77-2. |
| Q: What is the molecular formula of 7-Amino-1,2,3,4-tetrahydroisoquinoline? |
| A: Molecular formula of 7-Amino-1,2,3,4-tetrahydroisoquinoline is C9H12N2. |
| Q: What is the SMILES notation of 7-Amino-1,2,3,4-tetrahydroisoquinoline? |
| A: SMILES notation of 7-Amino-1,2,3,4-tetrahydroisoquinoline is Nc1ccc2c(c1)CNCC2. |
| Q: What English synonyms does 7-Amino-1,2,3,4-tetrahydroisoquinoline have? |
| A: English synonyms of 7-Amino-1,2,3,4-tetrahydroisoquinoline: 1,2,3,4-Tetrahydro-7-isoquinolinamine, 1,2,3,4-Tetrahydroisoquinolin-7-amine. |
| Q: What is the InChIKey of 7-Amino-1,2,3,4-tetrahydroisoquinoline? |
| A: InChIKey of 7-Amino-1,2,3,4-tetrahydroisoquinoline is VMEDBFRQSKKEEQ-UHFFFAOYSA-N. |
| Q: What is the polar surface area (PSA) of 7-Amino-1,2,3,4-tetrahydroisoquinoline? |
| A: Polar surface area (PSA) of 7-Amino-1,2,3,4-tetrahydroisoquinoline is 38.05000. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |