5-Bromo-2-Pyridinesulfonylchloride

Modify Date: 2026-07-09 18:04:11

5-Bromo-2-Pyridinesulfonylchloride Structure
5-Bromo-2-Pyridinesulfonylchloride structure
Common Name 5-Bromo-2-Pyridinesulfonylchloride
CAS Number 874959-68-9 Molecular Weight 256.505
Density 1.9±0.1 g/cm3 Boiling Point 301.0±22.0 °C at 760 mmHg
Molecular Formula C5H3BrClNO2S Melting Point N/A
MSDS USA Flash Point 135.8±22.3 °C

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 5-bromopyridine-2-sulfonyl chloride
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.9±0.1 g/cm3
Boiling Point 301.0±22.0 °C at 760 mmHg
Molecular Formula C5H3BrClNO2S
Molecular Weight 256.505
Flash Point 135.8±22.3 °C
Exact Mass 254.875626
PSA 55.41000
LogP 2.19
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.593
InChIKey CZPJXSLJOVFCOH-UHFFFAOYSA-N
SMILES O=S(=O)(Cl)c1ccc(Br)cn1

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

Material Safety Data Sheet

Section1. Identification of the substance
Product Name: 5-Bromo-pyridine-2-sulfonyl chloride
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.
H319:Causes serious eye irritation
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present
and easy to do – continue rinsing

Section3. Composition/information on ingredients.
Ingredient name:5-Bromo-pyridine-2-sulfonyl chloride
CAS number:874959-68-9

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Store in closed vessels, under −20◦C.
Storage:

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
Melting point:No data
Flash point:No data
Density:No data
Molecular formula:C5H3BrClNO2S
Molecular weight:256.5

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, hydrogen chloride, hydrogen bromide, sulfur
oxides.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

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5-Bromo-2-Pyridinesulfonylchloride Structure

5-Bromo-2-Pyrid...

CAS#:874959-68-9

Learn More
Literature: WO2008/2244 A2, ; Page/Page column 71-72 ; WO 2008/002244 A2

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5-Bromo-2-Pyridinesulfonylchloride Structure

5-Bromo-2-Pyrid...

CAS#:874959-68-9

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Literature: US2012/309796 A1, ; Page/Page column 25 ;

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5-Bromo-2-Pyridinesulfonylchloride Structure

5-Bromo-2-Pyrid...

CAS#:874959-68-9

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Literature: WO2007/93599 A1, ; Page/Page column 56; 57 ;

~%

5-Bromo-2-Pyridinesulfonylchloride Structure

5-Bromo-2-Pyrid...

CAS#:874959-68-9

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Literature: US2006/235028 A1, ; Page/Page column 27 ; US 20060235028 A1

~%

5-Bromo-2-Pyridinesulfonylchloride Structure

5-Bromo-2-Pyrid...

CAS#:874959-68-9

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Literature: WO2014/178 A1, ;

~%

5-Bromo-2-Pyridinesulfonylchloride Structure

5-Bromo-2-Pyrid...

CAS#:874959-68-9

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Literature: US2012/309796 A1, ;

 Precursor & DownStream

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor  6

DownStream  0

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

5-bromo-pyridine-2-sulfonyl chloride
5-bromo-pyridine-2-thiol
5-bromopyridine-2-sulfonyl chloride
5-Bromo-2-pyridinesulfonyl chloride
2-Pyridinesulfonyl chloride,5-bromo

 5-Bromo-2-Pyridinesulfonylchloride | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the polar surface area (PSA) of 5-bromopyridine-2-sulfonyl chloride?
A: Polar surface area (PSA) of 5-bromopyridine-2-sulfonyl chloride is 55.41000.
Q: What are the upstream materials of 5-bromopyridine-2-sulfonyl chloride?
A: Related upstream materials(CAS) of 5-bromopyridine-2-sulfonyl chloride: 874959-69-0;56673-34-8;223463-13-6;624-28-2;53939-30-3;13466-38-1.
Q: What is the SMILES notation of 5-bromopyridine-2-sulfonyl chloride?
A: SMILES notation of 5-bromopyridine-2-sulfonyl chloride is O=S(=O)(Cl)c1ccc(Br)cn1.
Q: What is the molecular weight of 5-bromopyridine-2-sulfonyl chloride?
A: Molecular weight of 5-bromopyridine-2-sulfonyl chloride is 256.505.
Q: What is the English name of 5-bromopyridine-2-sulfonyl chloride?
A: The English name of 5-bromopyridine-2-sulfonyl chloride is 5-bromopyridine-2-sulfonyl chloride.
Q: What is the boiling point of 5-bromopyridine-2-sulfonyl chloride?
A: Boiling point of 5-bromopyridine-2-sulfonyl chloride is 301.0±22.0 °C at 760 mmHg.
Q: What is the CAS number of 5-bromopyridine-2-sulfonyl chloride?
A: CAS number of 5-bromopyridine-2-sulfonyl chloride is 874959-68-9.
Q: What is the molecular formula of 5-bromopyridine-2-sulfonyl chloride?
A: Molecular formula of 5-bromopyridine-2-sulfonyl chloride is C5H3BrClNO2S.
Q: What is the LogP of 5-bromopyridine-2-sulfonyl chloride?
A: LogP of 5-bromopyridine-2-sulfonyl chloride is 2.19.
Q: What English synonyms does 5-bromopyridine-2-sulfonyl chloride have?
A: English synonyms of 5-bromopyridine-2-sulfonyl chloride: 5-bromo-pyridine-2-sulfonyl chloride, 5-bromo-pyridine-2-thiol, 5-bromopyridine-2-sulfonyl chloride, 5-Bromo-2-pyridinesulfonyl chloride, 2-Pyridinesulfonyl chloride,5-bromo.

 5-Bromo-2-Pyridinesulfonylchloridefactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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