IDO-IN-1
IDO-IN-1 structure
|
Common Name | IDO-IN-1 | ||
|---|---|---|---|---|
| CAS Number | 914638-30-5 | Molecular Weight | 316.08700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C9H7BrFN5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of IDO-IN-1IDO-IN-1 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 59 nM. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | IDO-IN-1 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 59 nM. |
|---|---|
| Related Catalog | |
| Target |
IDO:59 nM (IC50) IDO:12 nM (IC50, in HeLa cell) |
| In Vitro | IDO-IN-1 (Compound 5m) is a potent (HeLa IC50=12 nM) inhibitor of IDO[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C9H7BrFN5O2 |
|---|---|
| Molecular Weight | 316.08700 |
| Exact Mass | 314.97700 |
| PSA | 109.56000 |
| LogP | 2.45550 |
| InChIKey | ORHZJUSHZUCMKR-UHFFFAOYSA-N |
| SMILES | Nc1nonc1C(=Nc1ccc(F)c(Br)c1)NO |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| IDO-IN-1 |
| 4-amino-N(3-bromo-4-fluorophenyl)-N-hydroxy- |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the CAS number of 4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide? |
| A: CAS number of 4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide is 914638-30-5. |
| Q: What is the molecular formula of 4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide? |
| A: Molecular formula of 4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide is C9H7BrFN5O2. |
| Q: What is the SMILES notation of 4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide? |
| A: SMILES notation of 4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide is Nc1nonc1C(=Nc1ccc(F)c(Br)c1)NO. |
| Q: What is the InChIKey of 4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide? |
| A: InChIKey of 4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide is ORHZJUSHZUCMKR-UHFFFAOYSA-N. |
| Q: What English synonyms does 4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide have? |
| A: English synonyms of 4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide: IDO-IN-1, 4-amino-N(3-bromo-4-fluorophenyl)-N-hydroxy-. |
| Q: What is the LogP of 4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide? |
| A: LogP of 4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide is 2.45550. |
| Q: What are the uses of 4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide? |
| A: Main uses of 4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide: IDO-IN-1 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 59 nM. |
| Q: What is the polar surface area (PSA) of 4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide? |
| A: Polar surface area (PSA) of 4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide is 109.56000. |
| Q: What is the molecular weight of 4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide? |
| A: Molecular weight of 4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide is 316.08700. |
| Q: What is the English name of 4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide? |
| A: The English name of 4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide is 4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |