IDO-IN-2
Modify Date: 2025-08-25 08:47:31
IDO-IN-2 structure
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Common Name | IDO-IN-2 | ||
|---|---|---|---|---|
| CAS Number | 1668565-74-9 | Molecular Weight | 497.63 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H35N7O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of IDO-IN-2IDO-IN-2 is an IDO inhibitor extracted from patent WO/2015031295 A1, compound example 1, has IC50 values of 0.068 μM in HeLa cell and 0.16 μM in HEK293 cell. |
| Name | IDO-IN-2 |
|---|---|
| Synonym | More Synonyms |
| Description | IDO-IN-2 is an IDO inhibitor extracted from patent WO/2015031295 A1, compound example 1, has IC50 values of 0.068 μM in HeLa cell and 0.16 μM in HEK293 cell. |
|---|---|
| Related Catalog | |
| Target |
IDO:68 nM (IC50, in HeLa cell) IDO:160 nM (IC50, in HEK293 cell) |
| Molecular Formula | C29H35N7O |
|---|---|
| Molecular Weight | 497.63 |
| InChIKey | CJNMMPAEIYFQIJ-UHFFFAOYSA-N |
| SMILES | Cc1ccc(NC(=O)Nc2cc(-c3ccccc3-c3nn[nH]n3)ccc2N(CC(C)C)CC(C)C)cc1 |
| Storage condition | -20℃ |
| Water Solubility | DMSO: ≥ 31 mg/mL |
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Name: Stability in human liver microsomes assessed as half life
Source: ChEMBL
Target: N/A
External Id: CHEMBL5259456
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Name: Transactivation of PXR (unknown origin) relative to control
Source: ChEMBL
Target: Nuclear receptor subfamily 1 group I member 2
External Id: CHEMBL5259445
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Name: Transactivation of PXR (unknown origin)
Source: ChEMBL
Target: Nuclear receptor subfamily 1 group I member 2
External Id: CHEMBL5259441
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Name: Inhibition of CYP2C9 (unknown origin)
Source: ChEMBL
Target: Cytochrome P450 2C9
External Id: CHEMBL5259443
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Name: Metabolic stability in human liver microsomes assessed as compound remaining at 0.5 u...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5259438
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Name: Inhibition of TDO (unknown origin) expressed in HEK cells
Source: ChEMBL
Target: Tryptophan 2,3-dioxygenase
External Id: CHEMBL5259437
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Name: Metabolic stability in mouse liver microsomes assessed as compound remaining at 0.5 u...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5259440
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Name: Metabolic stability in rat liver microsomes assessed as compound remaining at 0.5 uM ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5259439
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Name: Primary qHTS for inhibitors of NSP2Pro chikungunya virus (CHIKV)
Source: NCGC
External Id: APP-Toga-CHIKV-nsp2-p
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Name: Inhibition of IDO1 (unknown origin) expressed in human HeLa cells
Source: ChEMBL
Target: Indoleamine 2,3-dioxygenase 1
External Id: CHEMBL5259436
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| IDO-IN2 |