Recombinant Human Hyaluronidase PH20
Published date: 2024-03-29 14:46:14
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Name | hyaluronidase | CAS# | 37259-53-3 |
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| Price | $Inquiry/1kg | Purity | 98.0% | |
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Inquiry | Stock | Inquiry | |
| Product Webpage: | https://ci.creativebiomart.net/recombinant-human-hyaluronidase-ph20-item-3996.html | |||
| Detail
Product Information
Cat:COS-PH20 Product Name:Recombinant Human Hyaluronidase PH20 Source:CHO Stable Cells Deion:Hyaluronidase PH-20 is also known as Sperm adhesion molecule 1 (SPAM1) and Sperm surface protein PH-20, which belongs to the glycosyl hydrolase 56 family, SPAM1 / PH-20 is expressed in testis. SPAM-1 / PH20 random hydrolysis of (1->4)-linkages between N – acetyl – beta – D – glucosamine and D-glucuronate residues in hyaluronate. SPAM-1 / PH20 involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. SPAM1 aids in penetrating the layer of cumulus cells by digesting hyaluronic acid. |