Ethoxylated hydrogenated castor oil
Ethoxylated hydrogenated castor oil structure
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Common Name | Ethoxylated hydrogenated castor oil | ||
|---|---|---|---|---|
| CAS Number | 61788-85-0 | Molecular Weight | 375.864 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 529.0±50.0 °C at 760 mmHg | |
| Molecular Formula | C21H23ClFNO2 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 273.8±30.1 °C | |
Use of Ethoxylated hydrogenated castor oilEthoxylated hydrogenated castor oil (PEG-40 hydrogenated castor oil) is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions. Ethoxylated hydrogenated castor oil can be used as a cosolvent in vivo[1]. |
| Name | Ethoxylated hydrogenated castor oil |
|---|---|
| Synonym | More Synonyms |
| Description | Ethoxylated hydrogenated castor oil (PEG-40 hydrogenated castor oil) is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions. Ethoxylated hydrogenated castor oil can be used as a cosolvent in vivo[1]. |
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| Related Catalog | |
| In Vivo | 20% PEG-40 hydrogenated castor oil (10 μl) is applied to the left ear of the mouse, and the right ear served as a control. The mice are observed for development of erthyma for 6 days, no signs of irritation are observed in the mice[1]. PEG-40 hydrogenated castor oil (injection via the tail vein; 300, 900, and 2700 mg/kg; 4 weeks) is administared for short-term toxicity. At doses of 300 and 900 mg/kg PEG-40 Hydrogenated Castor Oi exhibits no systemic toxicity. However, at a dose of 2700 mg/kg, slight ataxia is observed and body weight is reduced significantly in the males and slightly in the females[1]. A toxicity study of blank nanoemulsion using PEG-40 hydrogenated castor oil as a surfactant is applied in order to load various active compounds for oral administration[2]. Nearly 20% of PEG-40 hydrogenated castor oil was used to emulsify the glyceryl monooleate (GMO) as an oil to the aqueous phase. In Webster mice, 5000 mg/kg blank nanoemulsion is given orally to mice once a day for 14 days, this nanoemulsion does not produce hazardous effects, and it has no effect on food intake[2]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 529.0±50.0 °C at 760 mmHg |
| Molecular Formula | C21H23ClFNO2 |
| Molecular Weight | 375.864 |
| Flash Point | 273.8±30.1 °C |
| Exact Mass | 375.140137 |
| LogP | 3.01 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.581 |
| RIDADR | NONH for all modes of transport |
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Formulation and biopharmaceutical evaluation of silymarin using SMEDDS.
Arch. Pharm. Res. 30(1) , 82-9, (2007) Silymarin has been used to treat hepatobiliary diseases. However, it has a low bioavailability after being administered orally on account of its low solubility in water. In order to improve the dissol... |
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Preparation and evaluation of self-nanoemulsifying tablets of carvedilol.
AAPS PharmSciTech 10(1) , 183-92, (2009) The purpose of this study was to combine the advantages of self-nanoemulsifying drug delivery systems and tablets as a conventional dosage form emphasizing the excipients' effect on the development of... |
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Detailed molecular characterization of castor oil ethoxylates by liquid chromatography multistage mass spectrometry.
J. Chromatogr. A. 1218(40) , 7166-72, (2011) The molecular characterization of castor oil ethoxylates (CASEOs) was studied by reverse-phase liquid chromatography (RPLC) mass spectrometry (MS) and multistage mass spectrometry (MS(n)). The develop... |
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- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Ethoxylated hydrogenated castor oil
- Price: Check
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Ethoxylated hydrogenated castor oil
- Price: ￥188.0/250ml ￥78.0/25ml
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Liu jia
- Email: 2130147988@qq.com
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