Irbesartan

Published date: 2018-07-17 11:54:10

Irbesartan Structure
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Name Irbesartan CAS# 138402-11-6
Price $Inquiry/1kg Purity 99.9%
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 Detail Product Information
Names
[ Name ]: irbesartan
[ Synonym ]: More Synonyms
Chemical & Physical Properties
[ Density ]: 1.3±0.1 g/cm3
[ Boiling Point ]: 648.6±65.0 °C at 760 mmHg
[ Melting Point ]: 180-181°C
[ Molecular Formula ]: C25H28N6O
[ Molecular Weight ]: 428.529
[ Flash Point ]: 346.0±34.3 °C
[ Exact Mass ]: 428.232452
[ PSA ]: 87.13000
[ LogP ]: 4.51
[ Vapour Pressure ]: 0.0±1.9 mmHg at 25°C
[ Index of Refraction ]: 1.690
MSDS
Irbesartan MSDS(Chinese)
Safety Information
[ Hazard Codes ]: Xn: Harmful;
[ Risk Phrases ]: R22
[ Safety Phrases ]: S26-S36/37/39
[ RIDADR ]: 3276
[ Packaging Group ]: III
[ Hazard Class ]: 6.1
[ HS Code ]: 2933990090
Synthetic RoutePrevious 1/9 Next
3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2-thiophen-2-yl-1,3-diaza-spiro[4.4]non-1-en-4-one
1199814-92-0

3-[2'-(1H-t...

~82%

Irbesartan
138402-11-6

Irbesartan

Literature: RATIOPHARM GMBH Patent: WO2009/149734 A1, 2009 ; Location in patent: Page/Page column 14-15 ;
4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-[1,1'-Biphenyl]-2-carbonitrile
138401-24-8

4'-[(2-Buty...

~94%

Irbesartan
138402-11-6

Irbesartan

Literature: Satyanarayana, Bollikonda; Sumalatha, Yasareni; Sridhar, Chaganti; Venkatraman, Sundaram; Reddy, Padi Pratap Heterocyclic Communications, 2006 , vol. 12, # 5 p. 323 - 328
TRITYL IRBESARTAN
138402-10-5

TRITYL IRBESART...

~99%

Irbesartan
138402-11-6

Irbesartan

Literature: TEVA PHARMACEUTICAL INDUSTRIES LTD.; TEVA PHARMACEUTICALS USA, INC. Patent: WO2008/27385 A2, 2008 ; Location in patent: Page/Page column 21 ;
Precursor & DownStream
Precursor 8 Previous 1/2 Next
3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2-thiophen-2-yl-1,3-diaza-spiro[4.4]non-1-en-4-one Structure CAS#:1199814-92-0
3-[2'-(1H-tetra...
4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-[1,1'-Biphenyl]-2-carbonitrile Structure CAS#:138401-24-8
4'-[(2-Butyl-4-...
TRITYL IRBESARTAN Structure CAS#:138402-10-5
TRITYL IRBESARTAN
N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-1-[(1-oxopentyl)amino]cyclopentanecarboxamide Structure CAS#:141745-71-3
N-[(2'-Cyano[1,...
DownStream 1
5-(4'-Methyl-2-biphenylyl)-1H-tetrazole structure CAS#:120568-11-8
5-(4'-Methyl-2-...
Customs
[ HS Code ]: 2933990090
[ Summary ]: 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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[Irbesartan in clinical practice].
Kardiologiia 52(11) , 66-74, (2012)

Irbesartan is a noncompetitive angiotensin II receptor type 1 antagonist which has been successfully used for more than 10 years for the treatment of hypertensive disease. In a dose of 150-300 mg/day ...

Detail
Systemic sclerosis immunoglobulin induces growth and a pro-fibrotic state in vascular smooth muscle cells through the epidermal growth factor receptor.
PLoS ONE 9(6) , e100035, (2014)

It has been suggested that autoantibodies in systemic sclerosis (SSc) may induce the differentiation of cultured fibroblasts into myofibroblasts through platelet-derived growth factor receptor (PDGFR)...

Detail
Optimum AT1 receptor-neprilysin inhibition has superior cardioprotective effects compared with AT1 receptor blockade alone in hypertensive rats.
Kidney Int. 88 , 109-20, (2015)

Neprilysin inhibitors prevent the breakdown of bradykinin and natriuretic peptides, promoting vasodilation and natriuresis. However, they also increase angiotensin II and endothelin-1. Here we studied...

Detail
Synonyms
2-Butyl-3-{[2'-(1H-tetrazol-5-yl)-4-biphenylyl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one
Irbesartan
MFCD00864464
3-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one
3-Butyl-2-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-2,4-diazaspiro[4.4]non-3-en-1-one
1,3-Diazaspiro[4.4]non-1-en-4-one, 2-butyl-3-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
2-Butyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one
2-Butyl-3-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-1,3-diazaspiro[4.4]non-1-en-4-one
1,3-diazaspiro4.4non-1-en-4-one, 2-butyl-3-2'-(1H-tetrazol-5-yl)1,1'-biphenyl-4-ylmethyl-
2-butyl-3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one
Avapro
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JINAN DEPTONS CHEMICALl TECHNOLOGY CO. LTD

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Tel: 0532-80919617
Address: Room A408, no. 750, ShunHua Road, High-Tech Zone, Jinan city
Area: China
Contact: Angela
Contact Phone #: 18153243071
Email: bdlzhipin@aliyun.com
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